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Q41927879-453EE2C2-E8A8-4D71-8FBC-3918E24C6D13
Q41927879-453EE2C2-E8A8-4D71-8FBC-3918E24C6D13
BestRank
Statement
http://www.wikidata.org/entity/statement/Q41927879-453EE2C2-E8A8-4D71-8FBC-3918E24C6D13
M184I/V substitutions and E138K/M184I/V double substitutions in HIV reverse transcriptase do not significantly affect the antiviral activity of EFdA.
P2860
Q41927879-453EE2C2-E8A8-4D71-8FBC-3918E24C6D13
BestRank
Statement
http://www.wikidata.org/entity/statement/Q41927879-453EE2C2-E8A8-4D71-8FBC-3918E24C6D13
rank
NormalRank
type
BestRank
Statement
wasDerivedFrom
1b526051067f347a840b6828ba88fefbf2e8069e
P2860
Oral administration of the nucleoside EFdA (4'-ethynyl-2-fluoro-2'-deoxyadenosine) provides rapid suppression of HIV viremia in humanized mice and favorable pharmacokinetic properties in mice and the rhesus macaque