about
P688
NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage responsePARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repairThe histone demethylase LSD1/KDM1A promotes the DNA damage responseDistinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutantsFunctional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrestATM Kinase Is Required for Telomere Elongation in Mouse and Human CellsReactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1DNA damage-induced activation of p53 by the checkpoint kinase Chk2Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stagesSerine-threonine kinases and transcription factors active in signal transduction are detected at high levels of phosphorylation during mitosis in preimplantation embryos and trophoblast stem cellsRAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin lociAtm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous systemAnalysis of the relationships between ATM and the Rad54 paralogs involved in homologous recombination repairFunctional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombinationTargeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphomaDefective neurogenesis resulting from DNA ligase IV deficiency requires Atmp53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and PrkdcGenetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and developmentThe haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATRHeterozygous mutation of ataxia-telangiectasia mutated gene aggravates hypercholesterolemia in apoE-deficient miceSelective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system developmentThe mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with AtmCaspase-2 deficiency prevents programmed germ cell death resulting from cytokine insufficiency but not meiotic defects caused by loss of ataxia telangiectasia-mutated (Atm) gene functionDNA damage-induced G2/M checkpoint in SV40 large T antigen-immortalized embryonic fibroblast cells requires SHP-2 tyrosine phosphataseBRCA2 is required for neurogenesis and suppression of medulloblastomaAccumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient miceAtaxia telangiectasia mutated in cardiac fibroblasts regulates doxorubicin-induced cardiotoxicity.Ataxia Telangiectasia Mutated Dysregulation Results in Diabetic RetinopathyThe ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress.Global metabolomic responses in urine from atm deficient mice in response to LD gamma irradiation doses
P921
Q24323039-CF2F4FEE-3832-4007-9DBC-4F428E939663Q24337719-8FCF6655-8E21-4876-9166-4EFF21EF9087Q24339556-A9EAE336-93E1-4019-A517-F50FE54E8D80Q24557469-2AAC04E3-C86F-470D-8C4E-3F845B470DD3Q24677047-F2B0EFE1-B0E4-407C-B398-B5707A03AEC6Q28114948-E29A58C4-9846-4491-831E-25ABED0DBEF7Q28115279-66FC8B66-EB4A-4FD0-A9E6-CC378472832EQ28138195-803F81CA-8BBB-4B62-90EA-C0D01D5C6986Q28506028-D4309D2D-0306-46E6-AF37-7B2E89109368Q28508081-237F1869-67CC-46F5-8476-3B6EC16ADEBFQ28508203-0EFF8371-E9D9-4C75-99FB-60B3552A6DA9Q28508555-B6DEFD2C-5B7B-498B-AED4-4D4896D781AAQ28508601-0339AD35-E114-417D-8370-EA22C1988ED4Q28508673-45CF2BA8-BF43-43F7-B3A1-231B5D037DD2Q28509780-5B4691F0-1D17-4401-B0CD-F50460D4565FQ28510231-A1DF696F-CE6B-43F7-8087-25DAD11D23B0Q28510553-D92EA3E4-88A3-467E-A875-ABA82F1A4A3CQ28512255-73D93133-7C88-4440-98F3-F12FF3033432Q28512723-54E0183E-3CB9-4ABB-B955-6860614E3B58Q28585377-423DD986-BF01-4B9D-89A3-BFB2DD257BC1Q28585656-CD7BBA6C-0F55-4DEA-A923-8EF60FBEA6D4Q28586941-3063B7A1-901A-4B42-9138-553FD8DDAEBAQ28587062-C4B00728-FBF1-467A-9AD2-733284F4055DQ28590697-78CB936B-0514-4C7E-9C72-EB3DCE961465Q28590758-631F29BE-9D34-42B4-BE31-6DEBD01B83C0Q28593143-68D63FA0-CAE3-4D67-B630-22FDA681DBDDQ36702443-A64E4329-F159-4CAC-9F58-BA4C88894A80Q37445478-9136560A-B6EA-4171-8157-0962A7B56CBCQ42874810-9C25C2E6-6893-41E2-979A-07D7322021D7Q64122956-246113B6-AAA9-48E8-AB44-C7F11B97F457
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Ataxia telangiectasia mutated
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Ataxia telangiectasia mutated
@en
Ataxia telangiectasia mutated
@nl
type
label
Ataxia telangiectasia mutated
@en
Ataxia telangiectasia mutated
@nl
altLabel
A-T mutated homolog
@en
Atm
@en
ataxia telangiectasia gene mutated in human beings
@en
ataxia telangiectasia mutated homolog
@en
serine-protein kinase ATM
@en
prefLabel
Ataxia telangiectasia mutated
@en
Ataxia telangiectasia mutated
@nl
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ENSMUSP00000113388
ENSMUSP00000115394
ENSMUSP00000118199
ENSMUSP00000156344