about
P688
SOCS-6 negatively regulates T cell activation through targeting p56lck to proteasomal degradationLad, an adapter protein interacting with the SH2 domain of p56lck, is required for T cell activationFurther studies on hepatitis C virus NS5A-SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signallingInteraction of p56lck with CD4 in the yeast two-hybrid systemThe hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activityDemonstration of a direct interaction between p56lck and the cytoplasmic domain of CD45 in vitroInteraction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signalingCharacterization of Lnk. An adaptor protein expressed in lymphocytesLck availability during thymic selection determines the recognition specificity of the T cell repertoireImpaired development of V gamma 3 dendritic epidermal T cells in p56lck protein tyrosine kinase-deficient and CD45 protein tyrosine phosphatase-deficient miceThe CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lckInteractions between the amino-terminal domain of p56lck and cytoplasmic domains of CD4 and CD8 alpha in yeastDlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cellsCAML is a p56Lck-interacting protein that is required for thymocyte developmentGenetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptorPecam-1 is a modulator of stat family member phosphorylation and localization: lessons from a transgenic mouseRegulation of GATA-3 expression during CD4 lineage differentiation.HS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cellsStrong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signalingMouse CD24 as a signaling molecule for integrin-mediated cell binding: functional and physical association with src-kinasesSelective regulation of Lyn tyrosine kinase by CD45 in immature B cellsRegulation of T cell development by the deubiquitinating enzyme CYLDLKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selectionAssociation of CD45 with Lck and components of the Ras signalling pathway in pervanadate-treated mouse T-cell linesPEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cellsCD45 regulation of tyrosine phosphorylation and enzyme activity of src family kinasesCD45 and RPTPalpha display different protein tyrosine phosphatase activities in T lymphocytesThe phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck
P921
Q22001519-0AD3A6FA-3EE7-4C26-A765-07A107F2E3CFQ22010759-3BB85139-3080-4A4A-9134-87D28BF53C6DQ24298665-F0DBECA2-AFE9-4B74-A5C5-CFCC6CE25E51Q24303628-5F42927C-B74B-4983-9243-BA264C8924DAQ24313430-BFFBF733-C99C-440E-AA4A-18966C069782Q24318630-50015911-B8DE-4CFF-BEE2-F0081C31172FQ24322019-E49D0311-E01F-4DDC-B0E2-42E16731AAA5Q28239518-8F6CA282-58BC-46ED-A40F-5DE25AE8DBB7Q28298459-7CCB1627-9194-4562-B338-6028B0DE636EQ28504799-4E71D428-ED84-4C45-9B47-87E8E1F809EAQ28506433-8F68E15E-5000-4FDE-B1BD-19B66432C8FEQ28511524-46EE4B7A-A737-4E83-93A6-50068C1F3F5CQ28511680-E07F61E2-5615-4386-92F1-ED2311A380B5Q28511864-4C33986F-84BE-4DC7-8A1C-ECC360B07772Q28584997-2D66A14E-DD45-417C-A162-D3014C889EB0Q28585431-81910E18-CE93-4E5C-A270-A943671A594AQ28586757-28BC8461-3DA6-4FB6-8B75-D32C8D624D9CQ28586872-EA347537-A7A1-42FC-AFFA-F7EEEF20D39BQ28587210-F6FA29FD-7CA9-4323-9426-3D2377EDBE11Q28587389-62FDA8A2-8027-4DC4-B30B-3F67D1C1789BQ28588373-A5814FF6-4ED3-45C7-B59C-E8AE1A117C96Q28588773-2975547B-A5E9-41DC-B2BB-346B7E8345D5Q28589094-A629A31A-1AEB-4FBC-BF9D-1FF6955ACD3FQ28590124-9AA0060D-4CE1-465E-A4C7-F0619E9DA7AEQ28590230-E903F7A1-C37A-4B07-900E-9620B7AACF85Q28590919-2F236866-F3D0-4F83-B6D5-13821097024DQ28591137-A9ADEFE7-4E49-4B9C-BAE5-54BF0695BB15Q28591171-567BEDDB-F959-4680-85B1-CF44BA1A0C9A
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Lymphocyte protein tyrosine kinase
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
Lymphocyte protein tyrosine kinase
@en
Lymphocyte protein tyrosine kinase
@nl
type
label
Lymphocyte protein tyrosine kinase
@en
Lymphocyte protein tyrosine kinase
@nl
altLabel
LSK
@en
Lck
@en
leukocyte C-terminal Src kinase
@en
lymphocyte cell-specific protein-tyrosine kinase
@en
p56-LCK
@en
proto-oncogene tyrosine-protein kinase LCK
@en
prefLabel
Lymphocyte protein tyrosine kinase
@en
Lymphocyte protein tyrosine kinase
@nl
P361
P527
P637
P680
P681
P682
P705
P352
P486
P31
P352
P361
P486
P527
P637
NP_001155904
NP_001155905
XP_006502881
XP_030109135
XP_030109136
P680
P681
P682
P702
P703
P705
ENSMUSP00000066209
ENSMUSP00000099656
ENSMUSP00000119263
ENSMUSP00000125777