about
P688
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondriaBis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell deathMAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domainsBcl-2 family interaction with the mitochondrial morphogenesis machinerytBid undergoes multiple conformational changes at the membrane required for Bax activationProapoptotic BAX and BAK control multiple initiator caspasesProapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondriaA stapled BID BH3 helix directly binds and activates BAXDirect activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosisParkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell deathBcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell deathBID: a novel BH3 domain-only death agonistProapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alphaLoss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosisMale germ cells require polyenoic sphingolipids with complex glycosylation for completion of meiosis: a link to ceramide synthase-3Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosageBrn3a regulation of TrkA/NGF receptor expression in developing sensory neuronsInhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactionsCidea-deficient mice have lean phenotype and are resistant to obesityIntrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant miceGustatory innervation and bax-dependent caspase-2: participants in the life and death pathways of mouse taste receptor cellsTRPM-2 expression and tunel staining in neurodegenerative diseases: studies in wobbler and rd miceBcl-X(L)-caspase-9 interactions in the developing nervous system: evidence for multiple death pathwaysBcl-XL and Bcl-2 repress a common pathway of cell deathBax regulates primary necrosis through mitochondrial dynamicsGain of Bcl-2 is more potent than bax loss in regulating mammary epithelial cell survival in vivoProapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulumEnhanced oligodendrocyte survival after spinal cord injury in Bax-deficient mice and mice with delayed Wallerian degenerationMitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodelingBax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformationsUpregulation of Bcl2 inhibits apoptosis-driven BAX insertion but favors BAX relocalization in mitochondriaSpatial and temporal changes in Bax subcellular localization during anoikisBax and Bak independently promote cytochrome C release from mitochondriaElimination of Bax expression in mice increases cerebellar purkinje cell numbers but not the number of granule cellsNMDA receptors promote survival in somatosensory relay nuclei by inhibiting Bax-dependent developmental cell deathThe course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome cAtm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous systemBax-induced cytochrome c release from mitochondria depends on alpha-helices-5 and -6
P921
Q22008484-0CEA01D6-F46C-41D3-BEBE-BC9FEEE319D2Q22010927-86CA3174-9DD3-45CB-A3D8-28969E919A2BQ24290468-74D19873-7D9A-4D09-9FE2-9B1E6AC0AE9CQ24293601-AB734850-D70A-4C28-962B-263AE2DB6B2DQ24294675-0743F716-5126-4F70-9B61-A6C85F544787Q24298402-7B3F8F8F-EB9C-4756-BB1F-871F4B78B9A4Q24302494-50E1A70C-F223-408E-A303-72C688A284B2Q24306768-3248893F-955B-4F70-AF83-770DBBB8D003Q24307663-0243DC79-0606-4A98-8559-C062ECCC6436Q24307994-A9F49977-AEFC-475B-AE27-1230F9B2B44BQ24308897-4A109D6A-F59D-49CF-B9FB-8736B46B68E4Q24311298-5FEE66FB-A4E4-42E0-BAF1-3F86C2850752Q24312211-818F3308-A815-44C6-A343-EC24841305E4Q24320091-80EDDA8B-AA8E-47DB-8FA4-63A6293D77E3Q24322072-6FFFDE9F-C32B-4A78-8FA1-CAA667262404Q24534937-D51D4472-F2B8-4746-A300-9F0122E406D9Q24648735-7170C38D-EA29-4CFC-8FAA-54D6A61B7462Q24811545-1B48F392-BA30-4FB9-950E-FF4A44CB59D7Q28179688-8D5A825B-A611-4AEF-B56F-15EEE653C40FQ28283531-643D29FF-734D-4A86-BFEE-C94C4E2D1F52Q28504440-4BAA89EF-9A72-40C2-A4AC-539895265CF1Q28504500-C38EE4E9-0BA2-4568-939C-143C1AE9B000Q28504724-C0DF488B-219C-4146-9A78-C9132D8BC223Q28505012-59909A95-18DC-4D22-914A-E1DACF5ED9BDQ28505188-02BDC3A7-FF34-4DE0-814D-E578F13BFA01Q28505812-8220250A-750B-4D09-B3C4-C23B1C109224Q28506109-65DD0229-0632-4050-B5DD-B7FC31DA37BFQ28506179-A296ABF6-D8F6-4B42-91EA-5D0630F7E43AQ28506206-E236AD22-4F82-4A8B-A90F-F0E3F5845D47Q28506238-2B888486-C5FC-460E-9316-1103F2883FA0Q28506506-D50365E3-0C50-4AB1-ADF1-FBB740644116Q28506809-433D78AB-765D-4F8A-945D-524B52CB226FQ28507255-AC69482C-79D6-4A3A-837D-284948B6E97CQ28507532-983D4A12-3EF5-456D-9D23-7810AB048A21Q28507634-A5FA3D83-FA1F-4DC4-AFB7-5F6EE25EB9A6Q28507838-28F6A9B2-C40E-477E-A7AC-DEF043B1CB17Q28507944-74933DBD-B7BB-414F-BC99-2B293B7F8489Q28508087-87E9E3C4-0A6F-49C5-B953-C3E2AC25EC2CQ28508555-D04D6633-6543-48CD-80B3-56AD2A96A84CQ28509283-620F58AD-BFB0-464D-9E3D-20AC6D39B3C4
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in BCL2-associated X protein
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
BCL2-associated X protein
@en
BCL2-associated X protein
@nl
type
label
BCL2-associated X protein
@en
BCL2-associated X protein
@nl
altLabel
Bax
@en
apoptosis regulator BAX
@en
uniprot:Q07813
@en
prefLabel
BCL2-associated X protein
@en
BCL2-associated X protein
@nl
P527
P637
P680
P681
P682
P705
P352
P638
P31
P352
P527
P637
XP_006540647
XP_011249082
P680
P681
P682
P702
P703
P705
ENSMUSP00000033093
ENSMUSP00000147753
ENSMUSP00000148182
ENSMUSP00000148240
ENSMUSP00000148265