Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
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13-methyltetradecanoic acid exhibits anti-tumor activity on T-cell lymphomas in vitro and in vivo by down-regulating p-AKT and activating caspase-3Induction of Ankrd1 in Dilated Cardiomyopathy Correlates with the Heart Failure ProgressionProtection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting proteinDiva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell deathBax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondriaBoo, a novel negative regulator of cell death, interacts with Apaf-1.Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins.Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell deathAlternatively spliced products CC3 and TC3 have opposing effects on apoptosisApoptosis in myocardial ischaemia and infarctionBax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in vivo and in vitroStructural basis of BFL-1 for its interaction with BAX and its anti-apoptotic action in mammalian and yeast cellsCharacterization of MyD118, Gadd45, and proliferating cell nuclear antigen (PCNA) interacting domains. PCNA impedes MyD118 AND Gadd45-mediated negative growth controlMCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domainRole of S-nitrosylation in apoptosis resistance and carcinogenesisS-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation - a novel antiapoptotic mechanism that suppresses apoptosisInteraction of CR6 (GADD45gamma ) with proliferating cell nuclear antigen impedes negative growth controlBcl-G, a novel pro-apoptotic member of the Bcl-2 familyBcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extensionIron induces Bcl-2 expression in human dermal microvascular endothelial cellsVascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cellsCharacterization of fortilin, a novel antiapoptotic proteinBcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimersInteraction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosisAberrant expression of the transcription factors snail and slug alters the response to genotoxic stressProapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosisThe conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4Expression of galectin-3 modulates T-cell growth and apoptosisIdentification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspasesDimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteinsA common binding site mediates heterodimerization and homodimerization of Bcl-2 family membersDirect involvement of p53 in programmed cell death of oligodendrocytesBcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal developmentThe intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulumMutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosisThe p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/MWip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner
P2860
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P2860
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
description
1993 nî lūn-bûn
@nan
1993 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@ast
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@en
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@en-gb
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@nl
type
label
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@ast
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@en
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@en-gb
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@nl
prefLabel
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@ast
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@en
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@en-gb
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@nl
P2093
P921
P3181
P1433
P1476
Bcl-2 heterodimerizes in vivo ...... elerates programmed cell death
@en
P2093
C L Milliman
S J Korsmeyer
Z N Oltvai
P304
P3181
P356
10.1016/0092-8674(93)90509-O
P407
P577
1993-08-27T00:00:00Z