about
P688
Lyn is required for normal stem cell factor-induced proliferation and chemotaxis of primary hematopoietic cellsLyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitorsLeupaxin negatively regulates B cell receptor signalingMapping of sites on the Src family protein tyrosine kinases p55blk, p59fyn, and p56lyn which interact with the effector molecules phospholipase C-gamma 2, microtubule-associated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kGain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineageProcess outgrowth of oligodendrocytes is promoted by interaction of fyn kinase with the cytoskeletal protein tauLIME acts as a transmembrane adapter mediating BCR-dependent B-cell activationCritical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cellsFCRL5 exerts binary and compartment-specific influence on innate-like B-cell receptor signalingActivation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunitCEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complexRegulation of B-1 cell activation and its autoantibody production by Lyn kinase-regulated signallingsPositive and negative regulation of mast cell activation by Lyn via the FcepsilonRILiar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiationBinding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowthTargeting of MIST to Src-family kinases via SKAP55-SLAP-130 adaptor complex in mast cellsCharacterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulationGab3, a new DOS/Gab family member, facilitates macrophage differentiation.Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunityHS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cellsActivation of murine macrophages via TLR2 and TLR4 is negatively regulated by a Lyn/PI3K module and promoted by SHIP1Selective regulation of Lyn tyrosine kinase by CD45 in immature B cellsAn important role of the SRC family kinase Lyn in stimulating platelet granule secretionAltered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient miceMolecular cloning of the mouse APS as a member of the Lnk family adaptor proteinsThe Lyn tyrosine kinase differentially regulates dendritic cell generation and maturationFer kinase is required for sustained p38 kinase activation and maximal chemotaxis of activated mast cellsThe Src kinase Lyn is a negative regulator of mast cell proliferationFluorescence resonance energy transfer in living cells reveals dynamic membrane changes in the initiation of B cell signalingThe Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivoSCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophagesInvolvement of the Src kinase Lyn in phospholipase C-gamma 2 phosphorylation and phosphatidylinositol 3-kinase activation in Epo signalling.
P921
Q24291395-1CDC232C-935A-43E5-BDFC-590869FD353FQ24305025-29E598B5-49BE-4B3A-A3C4-97B8885337CAQ24321248-C382808C-7030-46CB-BC19-B07D75D85BE0Q24601358-AE6B1ABE-B943-4440-B71F-12EFB642FE55Q28201770-92D4AECB-2BA2-4CF2-BF64-A89157CAD4FFQ28217319-11C0A856-93BE-4852-A2CF-2485391C20B5Q28279011-CA636B30-CAAF-4C16-BC66-9A15033BBA28Q28505184-9C76E0C2-F0B4-4BC5-97DC-143931E54F27Q28506777-7380DC8B-A3F0-4954-98BC-334CD3E25276Q28508052-17C2553A-734F-4DCB-802C-4E23748725F3Q28509313-14D0F2B6-F436-401E-8FA3-9A450B446D26Q28509762-E4F5380E-5744-4ED5-8F5A-F7B847DBFD0FQ28510635-E4FA3F2F-BE21-4E5C-9FDA-34649EA7A41BQ28512258-4A453055-E55E-4D0A-BC24-89F861E89D41Q28575929-5BB46692-7356-42F9-BF61-368D892D64FDQ28582428-250E62CF-69D1-43CD-B50B-9E62C72A8BCDQ28584704-7E0F5603-D4AE-41DF-823C-10F585B9B03DQ28584713-97563E67-9964-4CB4-A3D9-67BD7382B095Q28585093-FDE25617-EF3E-41D8-8B6A-421A385A3EB9Q28586872-30184C6D-DD73-4456-AB17-789EFA2F7BE6Q28587460-FBE911FA-382F-47F5-9634-547A54F15F8AQ28588373-32D9BF1B-D068-4B47-A924-1EDCE5013BCDQ28588935-556C8683-3D10-4EF7-986E-7D742370D6E9Q28589721-6FD8909A-CB4D-4363-8991-FB832C093F27Q28591689-0DC3526F-092E-42CE-B3FB-240865330B41Q28592165-A92BDF7B-B963-4F19-A660-8A75D839BCBAQ28593250-437846F4-916A-4E0A-A522-D7C21A63C5ACQ28593549-2DF5CA70-90ED-4B75-A358-B5D36989C9E2Q34650209-26E1D281-513D-4670-8340-D8011AFF875FQ37114842-29C2CB30-9157-418A-B4E8-8CFB00DA3197Q37598447-23410399-AD37-46A3-B167-9C7BB7424183Q40680730-50C4BD99-6AD1-4A32-957D-FCBAE0AAEE28
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in LYN proto-oncogene, Src family tyrosine kinase
@nl
protèin
@ace
protéine
@fr
بروتين في فأر المنازل
@ar
name
LYN proto-oncogene, Src family tyrosine kinase
@en
type
label
LYN proto-oncogene, Src family tyrosine kinase
@en
altLabel
Lyn
@en
V-yes-1 Yamaguchi sarcoma viral related oncogene homolog
@en
Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
@en
p53Lyn
@en
p56Lyn
@en
tyrosine-protein kinase Lyn
@en
prefLabel
LYN proto-oncogene, Src family tyrosine kinase
@en
P361
P527
P637
P638
P680
P681
P682
P352
P31
P352
P361
P527
P637
NP_001104566
XP_030109145
P638
P680
P681
P682
P702
P703
P705
ENSMUSP00000038838
ENSMUSP00000100075