Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit
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Src-family tyrosine kinases in activation of ERK-1 and p85/p110-phosphatidylinositol 3-kinase by G/CCKB receptorsA phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cellsInteraction with PI3-kinase contributes to the cytotoxic activity of apoptinFunctional interaction between c-Src and its mitotic target, Sam 68Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59fyn in human T-lymphocytesBinding specificity and in vivo targets of the EH domain, a novel protein-protein interaction moduleA Ras-GTPase-activating protein SH3-domain-binding proteinG protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase.Shc adapter protein signaling complexesAutophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivoHuman spleen tyrosine kinase p72Syk associates with the Src-family kinase p53/56Lyn and a 120-kDa phosphoproteinActivation of phosphoinositide 3-kinase by interaction with Ras and by point mutationInhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cellsMutational analysis of the Src SH3 domain: the same residues of the ligand binding surface are important for intra- and intermolecular interactionsNegative regulation of PI 3-kinase by Ruk, a novel adaptor proteinIntegrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinaseLeukocyte migration from a fish eye's viewCrystal structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 alpha subunitThe Src homology domain 3 (SH3) of a yeast type I myosin, Myo5p, binds to verprolin and is required for targeting to sites of actin polarizationVesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeastA novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinaseHeregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptorA rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivoA role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesionsSos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptorsProline-rich sequences that bind to Src homology 3 domains with individual specificitiesAssociation of 75/80-kDa phosphoproteins and the tyrosine kinases Lyn, Fyn, and Lck with the B cell molecule CD20. Evidence against involvement of the cytoplasmic regions of CD20PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cellsRegulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunitDasatinib inhibits CXCR4 signaling in chronic lymphocytic leukaemia cells and impairs migration towards CXCL12Association of PI3K-Akt signaling pathway with digitalis-induced hypertrophy of cardiac myocytesPhosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical laminationCloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinaseErbB4 expression in neural progenitor cells (ST14A) is necessary to mediate neuregulin-1beta1-induced migrationPhosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinaseTemporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagementQualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilizationAssembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer.Role of hepatitis B virus X protein in regulating LIM and SH3 protein 1 (LASP-1) expression to mediate proliferation and migration of hepatoma cellsLocalization of Tec29 to ring canals is mediated by Src64 and PtdIns(3,4,5)P3-dependent mechanisms.Phosphatidylinositol 3-kinase p85 adaptor function in T-cells. Co-stimulation and regulation of cytokine transcription independent of associated p110.
P2860
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P2860
Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit
description
1994 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 1994
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im März 1994 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 1994/03/18)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/03/18)
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наукова стаття, опублікована в березні 1994
@uk
name
Activation of phosphatidylinos ...... SH3 binding to the p85 subunit
@ast
Activation of phosphatidylinos ...... SH3 binding to the p85 subunit
@en
Activation of phosphatidylinos ...... SH3 binding to the p85 subunit
@nl
type
label
Activation of phosphatidylinos ...... SH3 binding to the p85 subunit
@ast
Activation of phosphatidylinos ...... SH3 binding to the p85 subunit
@en
Activation of phosphatidylinos ...... SH3 binding to the p85 subunit
@nl
prefLabel
Activation of phosphatidylinos ...... SH3 binding to the p85 subunit
@ast
Activation of phosphatidylinos ...... SH3 binding to the p85 subunit
@en
Activation of phosphatidylinos ...... SH3 binding to the p85 subunit
@nl
P2093
P356
P1433
P1476
Activation of phosphatidylinos ...... SH3 binding to the p85 subunit
@en
P2093
C. M. Pleiman
J. C. Cambier
W. M. Hertz
P304
P356
10.1126/SCIENCE.8128248
P407
P577
1994-03-18T00:00:00Z