about
P688
Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHRRoles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targettingThe kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation sitePhosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA bindingThe PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3Novel repressor regulates insulin sensitivity through interaction with Foxo1Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activityGAS6-induced signaling in human endothelial cells is mediated by FOXO1aFoxM1, a critical regulator of oxidative stress during oncogenesisMARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels.
P921
Q50255944-5821A9F4-B3A1-4A1A-851D-0F476642BFE5Q50255945-13807760-C5CD-4F03-92BF-814608BEA0F7Q50263051-01B054BA-E4F6-4655-BCF1-2523200B3F80Q50287847-3DC48CD8-3956-44C8-A684-4F5FB338578DQ50287848-09838757-9C96-4F44-8F7B-06C9B3A435C1Q50287848-35798595-6D5E-48D4-947D-44C39AA49C3AQ50287851-3CF5C36F-DB42-4F2C-A132-9010AA0510ACQ50299042-4293161E-A45C-4D70-A948-0080EA052F94
P527
Q22254411-574FEFDC-6D34-477C-8F9A-26BAED5B0FD3Q24290893-F9A0B667-2F16-47F3-B14F-4C228E64B8C3Q24291137-B0CCB89F-8489-4577-ACC8-F719E4C2FF88Q24306703-7BBC3A11-B113-4E49-AD1B-AA51B46A57C8Q24313754-31C839E5-7072-454A-AD14-34660128C90FQ24314731-2D354E45-AD26-4807-9D4C-829A67ED3266Q24320035-366E3BD7-2EB3-4C0F-88D8-26B026909007Q24321260-68C53035-29CB-4AD9-AB44-3A54D1BBDA06Q24336836-00DD3C6C-E29C-491D-AD64-B668BF39B41AQ37237315-C4B6F594-E6F6-4652-88DA-70CDB9466B32
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Forkhead box O1
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
Forkhead box O1
@en
type
label
Forkhead box O1
@en
altLabel
FOXO1
@en
Forkhead in rhabdomyosarcoma
@en
forkhead box protein O1
@en
forkhead box protein O1A
@en
forkhead, Drosophila, homolog of, in rhabdomyosarcoma
@en
prefLabel
Forkhead box O1
@en
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D000071161
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XP_011533310
XP_011533312
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ENSP00000368880