FoxM1, a critical regulator of oxidative stress during oncogenesis
about
FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesisA systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cellsDisabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant MesotheliomaStructure of the FoxM1 DNA-recognition domain bound to a promoter sequenceFOXM1 in sarcoma: role in cell cycle, pluripotency genes and stem cell pathwaysFOXM1 is an oncogenic mediator in Ewing SarcomaPeroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cellsRecent advances of highly selective CDK4/6 inhibitors in breast cancerForkhead box M1 transcription factor: a novel target for cancer therapy.FoxM1B regulates NEDD4-1 expression, leading to cellular transformation and full malignant phenotype in immortalized human astrocytesCDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers.RETRACTED: DDB2, an essential mediator of premature senescenceIncreased FOXM1 expression can stimulate DNA repair in normal hepatocytes in vivo but also increases nuclear foci associated with senescence.FoxM1 mediates resistance to herceptin and paclitaxel.Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.FoxM1 is a novel target of a natural agent in pancreatic cancer.Differential response of normal (PrEC) and cancerous human prostate cells (PC-3) to phenethyl isothiocyanate-mediated changes in expression of antioxidant defense genes.Negative regulation of the oncogenic transcription factor FoxM1 by thiazolidinediones and mithramycin.SRp20 is a proto-oncogene critical for cell proliferation and tumor induction and maintenance.Endothelial cell-specific deletion of transcription factor FoxM1 increases urethane-induced lung carcinogenesis.ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitorsAromatic amino acid activation of signaling pathways in bone marrow mesenchymal stem cells depends on oxygen tensionIdentification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia.Phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin (PI3K-Akt-mTOR) signaling pathway in non-small cell lung cancerp21 cooperates with DDB2 protein in suppression of ultraviolet ray-induced skin malignancies.Investigation of FOXM1 as a Potential New Target for Melanoma.Essential roles of FoxM1 in Ras-induced liver cancer progression and in cancer cells with stem cell features.Hypoxia-induced pulmonary arterial smooth muscle cell proliferation is controlled by forkhead box M1.Deregulation of FoxM1b leads to tumour metastasis.7-difluoromethoxyl-5,4'-di-n-octylgenistein inhibits growth of gastric cancer cells through downregulating forkhead box M1.Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epitheliumThe requirement for cyclin D function in tumor maintenance.Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare MutationsThe critical role of dysregulated FOXM1-PLAUR signaling in human colon cancer progression and metastasis.Forkhead box M1 is regulated by heat shock factor 1 and promotes glioma cells survival under heat shock stressFOXM1b, which is present at elevated levels in cancer cells, has a greater transforming potential than FOXM1c.Tumor regression by phenethyl isothiocyanate involves DDB2.Novel functions of FoxM1: from molecular mechanisms to cancer therapyPKCι counteracts oxidative stress by regulating Hsc70 in an esophageal cancer cell line.Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells.
P2860
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P2860
FoxM1, a critical regulator of oxidative stress during oncogenesis
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
FoxM1, a critical regulator of oxidative stress during oncogenesis
@ast
FoxM1, a critical regulator of oxidative stress during oncogenesis
@en
FoxM1, a critical regulator of oxidative stress during oncogenesis
@en-gb
FoxM1, a critical regulator of oxidative stress during oncogenesis
@nl
type
label
FoxM1, a critical regulator of oxidative stress during oncogenesis
@ast
FoxM1, a critical regulator of oxidative stress during oncogenesis
@en
FoxM1, a critical regulator of oxidative stress during oncogenesis
@en-gb
FoxM1, a critical regulator of oxidative stress during oncogenesis
@nl
prefLabel
FoxM1, a critical regulator of oxidative stress during oncogenesis
@ast
FoxM1, a critical regulator of oxidative stress during oncogenesis
@en
FoxM1, a critical regulator of oxidative stress during oncogenesis
@en-gb
FoxM1, a critical regulator of oxidative stress during oncogenesis
@nl
P2093
P2860
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P3181
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FoxM1, a critical regulator of oxidative stress during oncogenesis
@en
P2093
Hyun Jung Park
Lester F Lau
Nissim Hay
Pradip Raychaudhuri
Robert H Costa
Veronique Nogueira
Zebin Wang
P2860
P304
P3181
P356
10.1038/EMBOJ.2009.239
P407
P577
2009-10-07T00:00:00Z