Can animal models of disease reliably inform human studies? - sprookjes - yvandenbroek - TriplyDB

Can animal models of disease reliably inform human studies?

Can animal models of disease reliably inform human studies?

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Improving basic and translational science by accounting for litter-to-litter variation in animal models Prospects for Improving Brain Function in Individuals with Down Syndrome A preclinical physiological assay to test modulation of knee joint pain in the spinal cord: effects of oxycodone and naproxen Where Have All the Rodents Gone? The Effects of Attrition in Experimental Research on Cancer and Stroke Open science and reporting animal studies: who's accountable?Do stroke models model stroke?The methodological quality of animal research in critical care: the public face of science Lost in Translation (LiT): IUPHAR Review 6 A combined pre-clinical meta-analysis and randomized confirmatory trial approach to improve data validity for therapeutic target validation A call for transparent reporting to optimize the predictive value of preclinical research The evolution of traumatic brain injury in a rat focal contusion model Systematic reviews of animal models: methodology versus epistemology.Microfluidic organ-on-chip technology for blood-brain barrier research Efficacy of Mesenchymal Stromal Cell Therapy for Acute Lung Injury in Preclinical Animal Models: A Systematic Review The Snark was a Boojum - reloaded Neuroprotective Strategies after Neonatal Hypoxic Ischemic Encephalopathy Translational challenges of animal models in Chagas disease drug development: a review Animal models of diabetic macrovascular complications: key players in the development of new therapeutic approaches Refinement of Experimental Design and Conduct in Laboratory Animal Research Critical appraisal of studies using laboratory animal models Experimental primates and non-human primate (NHP) models of human diseases in China: current status and progress Modelling human disease with pluripotent stem cells Effect of endothelin receptor antagonists on clinically relevant outcomes after experimental subarachnoid hemorrhage: a systematic review and meta-analysis A conceptual and practical guide to the behavioural evaluation of animal models of the symptomatology and therapy of schizophrenia.The significance of meaning: why do over 90% of behavioral neuroscience results fail to translate to humans, and what can we do to fix it?Wnt signaling in neuropsychiatric disorders: ties with adult hippocampal neurogenesis and behavior Progress in the genetics of polygenic brain disorders: significant new challenges for neurobiology Therapeutic neuroprotective agents for amyotrophic lateral sclerosis Nephropathic cystinosis: an international consensus document Translational spinal cord injury research: preclinical guidelines and challenges A step-by-step guide to systematically identify all relevant animal studies Improving the predictive value of interventional animal models data Controlling complexity: the clinical relevance of mouse complex genetics Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis Derivation of multivariate syndromic outcome metrics for consistent testing across multiple models of cervical spinal cord injury in rats Monitoring the Growth of an Orthotopic Tumour Xenograft Model: Multi-Modal Imaging Assessment with Benchtop MRI (1T), High-Field MRI (9.4T), Ultrasound and Bioluminescence.MicroRNAs for osteosarcoma in the mouse: a meta-analysis Zebrafish small molecule screens: Taking the phenotypic plunge Animal Models in Cardiovascular Research: Hypertension and Atherosclerosis

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Can animal models of disease reliably inform human studies?

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2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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Can animal models of disease reliably inform human studies?

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Publication bias in reports of animal stroke studies leads to major overstatement of efficacy

Launching invasive, first-in-human trials against Parkinson's disease: ethical considerations

Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials

Clinical practice. Acute ischemic stroke

Design, power, and interpretation of studies in the standard murine model of ALS

1,026 experimental treatments in acute stroke

Systematic reviews in health care: Assessing the quality of controlled clinical trials

The revised CONSORT statement for reporting randomized trials: explanation and elaboration

Systematic review of the empirical evidence of study publication bias and outcome reporting bias

Pooling of animal experimental data reveals influence of study design and publication bias.

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