about
P688
Identification and mechanism of action of the acylguanidine MRT-83, a novel potent Smoothened antagonistThe hedgehog receptor patched is involved in cholesterol transportA phenotype-based screen for embryonic lethal mutations in the mouse.Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in miceZfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium FunctionWdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeletonVertebrate Smoothened functions at the primary cilium.Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferationDivergence of hedgehog signal transduction mechanism between Drosophila and mammalsHepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levelsIsl1 is upstream of sonic hedgehog in a pathway required for cardiac morphogenesisIntraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway componentsMouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signalingGLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesisSonic hedgehog signaling regulates the expression of insulin-like growth factor binding protein-6 during fetal prostate developmentThe IFT-A complex regulates Shh signaling through cilia structure and membrane protein traffickingAutonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formationYAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferationThe primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiationIhh signaling is directly required for the osteoblast lineage in the endochondral skeletonThe level of sonic hedgehog signaling regulates the complexity of cerebellar foliationTbx5-hedgehog molecular networks are essential in the second heart field for atrial septationHedgehog induction of murine vasculogenesis is mediated by Foxf1 and Bmp4Hedgehog-regulated localization of Vax2 controls eye developmentSmoothened controls cyclin D2 expression and regulates the generation of intermediate progenitors in the developing cortexSonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain regionHedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult beta-cell functionHedgehog signaling and primary cilia are required for the formation of adult neural stem cellsTubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signalingSox17 regulates organ lineage segregation of ventral foregut progenitor cellsShh signaling within the dental epithelium is necessary for cell proliferation, growth and polarizationalphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathwayCilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conservedA direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cordHedgehog signaling is essential for endothelial tube formation during vasculogenesisSonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowthIntraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblastsAbnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signalingProgenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activityLoss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli
P921
Q24319081-F62DAB48-151A-475E-A7B2-062DF55C8FD8Q24338297-072EA1F2-3822-403D-ADA9-4E5DC070DE2CQ24655452-4AE65D5C-D111-41EE-ADC3-B76E95208AAAQ24658398-44D36699-9A0D-463E-8710-A49EC6CE79B1Q27307807-7A4AE4A9-BFDA-46D9-A589-DDFB457BCAC7Q27316402-82054CA5-26C3-4A6D-A3F3-0D99FAD9FB29Q27919682-CD5712DA-B62F-45ED-BCBB-BA8F1482F611Q28211798-8DC02D9C-5000-4303-A9E0-6BEBEBACB3BAQ28295678-96FE4B2B-6508-47AB-A261-6A1F0BF8F103Q28504728-FEFD1F34-47B3-472B-AA3A-0CC23A8C5AF3Q28504915-F8427CEB-B829-437B-B756-811E5DFF1D56Q28505068-AEC0AB09-0D21-4BE6-AD66-F959709D4633Q28505317-AB1F5690-FF08-4D92-841B-CA03E010951CQ28505774-120076F4-95E8-4994-899C-CD6C7EAA3FA3Q28506007-5F7A2230-A2A7-48F5-9BD5-F79066EE32C6Q28506316-C1CA93A2-48DE-45D9-97B2-E688F6F6AB98Q28507041-DE9062B5-3F2F-4C87-8868-A59D010F4BDCQ28507494-11422834-4DE4-4F25-A8D8-FD2CF167F3EAQ28507794-32ACF824-3D2C-4109-90B8-D67D74C54F3AQ28508641-EC924493-1BB9-4EFE-9551-EA8D335A3405Q28508934-CC6DBF2F-76E5-4862-81CF-3C8CC154890BQ28509085-B0342FE2-3B93-4976-8D48-02E582B16900Q28509389-2A3E7939-506A-40D8-8574-00F168B0E81FQ28509927-D267C4B1-AE33-4832-BB4A-2E0DD90219C4Q28511154-94CF99DC-1532-4216-A436-572259D9B283Q28511592-74CFEA58-F1F6-4DF9-913E-32D52427EF2FQ28512200-D6874CDC-52B9-4F0B-829D-7E590864FF16Q28512856-960174EF-FB3B-495C-AF3A-7610B06A87ABQ28512967-6C949AF6-E3EF-464B-AFC2-E685FF021D9FQ28513551-E3AA1F85-65CC-4CE8-A5FC-4CEEEC97D926Q28584875-70625767-7D0A-4635-98FA-502E912664E7Q28585721-114F58AA-E08C-4FBA-BB57-9A1943BF68CFQ28585804-59E1F7C8-7C47-4FCC-A07D-7B45876E7CBCQ28586729-F75E2773-FDE5-459F-B610-2C26D03345CFQ28587747-57377285-E764-448F-8996-2A87947B2D89Q28590687-E5DC74A4-2ACC-401F-A0B5-804184568C89Q28591555-212C3F77-8AFC-4C9B-857C-6F6E30F2CFD1Q28592404-F2DB3A3D-30F5-4B85-A36A-3228B921B46BQ28592781-4150BF36-4A4D-44BE-B623-398D55F7ED2EQ28593401-8B713091-4F4B-46BA-9AD6-122D04E78B0A
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Smoothened, frizzled class receptor
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Smoothened, frizzled class receptor
@en
type
label
Smoothened, frizzled class receptor
@en
altLabel
Smo
@en
bent body
@en
smoothened homolog
@en
prefLabel
Smoothened, frizzled class receptor
@en
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XP_006505169
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ENSMUSP00000001812