Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli
about
The dynamic cilium in human diseasesHuman and mouse mutations in WDR35 cause short-rib polydactyly syndromes due to abnormal ciliogenesisThe spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesisThe Zn finger protein Iguana impacts Hedgehog signaling by promoting ciliogenesisThe Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formationNEK1 mutations cause short-rib polydactyly syndrome type majewskiThe antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathwayGli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal diseaseMechanisms of nephronophthisis and related ciliopathiesCiliary abnormalities due to defects in the retrograde transport protein DYNC2H1 in short-rib polydactyly syndromeDifferential role of Hedgehog signaling in human pancreatic (patho-) physiology: An up to date reviewIns and outs of GPCR signaling in primary ciliaCilia in vertebrate development and diseaseCilia/Ift protein and motor -related bone diseases and mouse modelsZfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium FunctionConserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary SignalingAssembly of IFT trains at the ciliary base depends on IFT74The nonmotile ciliopathies.The BBSome controls IFT assembly and turnaround in cilia.Disruption of a ciliary B9 protein complex causes Meckel syndromeDYNC2LI1 mutations broaden the clinical spectrum of dynein-2 defectsCilia and developmental signalingKif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesisMechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loadingTHM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in ciliaTtc21b is required to restrict sonic hedgehog activity in the developing mouse forebrainAn Ift80 mouse model of short rib polydactyly syndromes shows defects in hedgehog signalling without loss or malformation of ciliaHippi is essential for node cilia assembly and Sonic hedgehog signalingMouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathwayRole of epidermal primary cilia in the homeostasis of skin and hair folliclesA mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signalingFunctional characterization of putative cilia genes by high-content analysisThe primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiationForward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signalingIntraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brainTemporal deletion of Arl13b reveals that a mispatterned neural tube corrects cell fate over timeIFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transportComplex interactions between genes controlling trafficking in primary ciliaProtein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube
P2860
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P2860
Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli
description
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im November 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/11/15)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/11/15)
@nl
наукова стаття, опублікована в листопаді 2005
@uk
مقالة علمية (نشرت في 15-11-2005)
@ar
name
Loss of the retrograde motor f ...... and repressor functions of Gli
@ast
Loss of the retrograde motor f ...... and repressor functions of Gli
@en
Loss of the retrograde motor f ...... and repressor functions of Gli
@nl
type
label
Loss of the retrograde motor f ...... and repressor functions of Gli
@ast
Loss of the retrograde motor f ...... and repressor functions of Gli
@en
Loss of the retrograde motor f ...... and repressor functions of Gli
@nl
prefLabel
Loss of the retrograde motor f ...... and repressor functions of Gli
@ast
Loss of the retrograde motor f ...... and repressor functions of Gli
@en
Loss of the retrograde motor f ...... and repressor functions of Gli
@nl
P2093
P3181
P1476
Loss of the retrograde motor f ...... and repressor functions of Gli
@en
P2093
Amir M. Ashique
Andrew S. Peterson
Baolin Wang
Jeremy Reiter
Kostantinos Zarbalis
Mattias Karlen
Scott R. May
Yiguo Shen
P304
P3181
P356
10.1016/J.YDBIO.2005.08.050
P407
P577
2005-11-15T00:00:00Z