HIV-1 Nef impairs MHC class II antigen presentation and surface expression
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Direct binding of human immunodeficiency virus type 1 Nef to the major histocompatibility complex class I (MHC-I) cytoplasmic tail disrupts MHC-I traffickingRab27a and Rab27b control different steps of the exosome secretion pathwayMajor histocompatibility complex class II-peptide complexes internalize using a clathrin- and dynamin-independent endocytosis pathwayHuman immunodeficiency virus type 1 Vpu protein interacts with CD74 and modulates major histocompatibility complex class II presentationTherapeutic targets for HIV-1 infection in the host proteome.Remodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and PersistenceInfluence of HIV and HCV on T cell antigen presentation and challenges in the development of vaccinesOropharyngeal Candidiasis in HIV Infection: Analysis of Impaired Mucosal Immune Response to Candida albicans in Mice Expressing the HIV-1 TransgeneInnate immune recognition of HIV-1One protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef.Human leukocyte antigens and HIV type 1 viral load in early and chronic infection: predominance of evolving relationshipsA consensus surface activation marker signature is partially dependent on human immunodeficiency virus type 1 Nef expression within productively infected macrophagesHIV and Tuberculosis: a Deadly Human SyndemicEfficient Vpu-Mediated Tetherin Antagonism by an HIV-1 Group O Strain.In Vivo and in Vitro Proteome Analysis of Human Immunodeficiency Virus (HIV)-1-infected, Human CD4+ T Cells.HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo.Naturally-acquired influenza-specific CD4+ T-cell proliferative responses are impaired in HIV-infected African adults.Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infectionHIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells.Immunosuppression during acute infection with foot-and-mouth disease virus in swine is mediated by IL-10.Preserved MHC class II antigen processing in monocytes from HIV-infected individualsSingle vector system for efficient N-myristoylation of recombinant proteins in E. coli.Human immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism.Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinaseHIV-1 Nef Signaling in Intestinal Mucosa Epithelium Suggests the Existence of an Active Inter-kingdom Crosstalk Mediated by Exosomes.Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1.Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication.Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabetaCounteraction of HLA-C-mediated immune control of HIV-1 by Nef.HIV-1 Nef binds a subpopulation of MHC-I throughout its trafficking itinerary and down-regulates MHC-I by perturbing both anterograde and retrograde trafficking.HIV-1 Nef enhances dendritic cell-mediated viral transmission to CD4+ T cells and promotes T-cell activation.Modulation of cellular protein trafficking by human immunodeficiency virus type 1 Nef: role of the acidic residue in the ExxxLL motif.Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptorsGenomic analysis reveals pre- and postchallenge differences in a rhesus macaque AIDS vaccine trial: insights into mechanisms of vaccine efficacyThe presence of a vpu gene and the lack of Nef-mediated downmodulation of T cell receptor-CD3 are not always linked in primate lentivirusesMultiple low-dose challenges in a rhesus macaque AIDS vaccine trial result in an evolving host response that affects protective outcomeNef proteins from simian immunodeficiency viruses are tetherin antagonists.Lessons from viral manipulation of protein disposal pathwaysIntra- and intersubtype alternative Pak2-activating structural motifs of human immunodeficiency virus type 1 NefMisdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence.
P2860
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P2860
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
@ast
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
@en
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
@nl
type
label
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
@ast
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
@en
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
@nl
prefLabel
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
@ast
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
@en
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
@nl
P2093
P2860
P356
P1476
HIV-1 Nef impairs MHC class II antigen presentation and surface expression
@en
P2093
Morchoisne S
Schwartz O
Stumptner-Cuvelette P
P2860
P304
12144-12149
P356
10.1073/PNAS.221256498
P407
P577
2001-10-02T00:00:00Z