Identification of Mrj, a DnaJ/Hsp40 family protein, as a keratin 8/18 filament regulatory protein
about
Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADDCharacterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independentlyERBIN associates with p0071, an armadillo protein, at cell-cell junctions of epithelial cellsBreast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperoneMutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophyThe keratin-binding protein Albatross regulates polarization of epithelial cellsThe DnaJ-related factor Mrj interacts with nuclear factor of activated T cells c3 and mediates transcriptional repression through class II histone deacetylase recruitmentDNAJB6 Myopathies: Focused Review on an Emerging and Expanding Group of MyopathiesMultiple roles for keratin intermediate filaments in the regulation of epithelial barrier function and apico-basal polarityDensin-180 interacts with delta-catenin/neural plakophilin-related armadillo repeat protein at synapsesCell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental developmentImpaired placental trophoblast lineage differentiation in Alkbh1(-/-) miceHeat shock proteins: cellular and molecular mechanisms in the central nervous system.Hsp40 facilitates nuclear import of the human immunodeficiency virus type 2 Vpx-mediated preintegration complexIntermediate filaments take the heat as stress proteins.DNAJB6 induces degradation of beta-catenin and causes partial reversal of mesenchymal phenotype.The BAG-1 isoform BAG-1M regulates keratin-associated Hsp70 chaperoning of aPKC in intestinal cells during activation of inflammatory signaling.Keratins: guardians of the liver.Methylation-controlled J protein promotes c-Jun degradation to prevent ABCB1 transporter expression.PDK1 in apical signaling endosomes participates in the rescue of the polarity complex atypical PKC by intermediate filaments in intestinal epithelia.Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1DKeratin K18 increases cystic fibrosis transmembrane conductance regulator (CFTR) surface expression by binding to its C-terminal hydrophobic patch.Large isoform of MRJ (DNAJB6) reduces malignant activity of breast cancer.Functional Analysis of Keratin-Associated Proteins in Intestinal Epithelia: Heat-Shock Protein Chaperoning and Kinase RescueStructure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia.Emerging roles and underlying molecular mechanisms of DNAJB6 in cancerOverexpression of DNAJB6 promotes colorectal cancer cell invasion through an IQGAP1/ERK-dependent signaling pathway.Asymmetrical cell division and differentiation are not dependent upon stratification in a corneal epithelial cell line.Myopathy in Marinesco-Sjögren syndrome links endoplasmic reticulum chaperone dysfunction to nuclear envelope pathology.HSP40s activate intrinsic ATPase activity of HSP70s in the cytosolStructural modelling of the DNAJB6 oligomeric chaperone shows a peptide-binding cleft lined with conserved S/T-residues at the dimer interface.
P2860
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P248
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P2860
Identification of Mrj, a DnaJ/Hsp40 family protein, as a keratin 8/18 filament regulatory protein
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2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@ast
Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@en
Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@en-gb
Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@nl
type
label
Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@ast
Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@en
Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@en-gb
Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@nl
prefLabel
Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@ast
Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@en
Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@en-gb
Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@nl
P2093
P2860
P3181
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P1476
Identification of Mrj, a DnaJ/ ...... 18 filament regulatory protein
@en
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P2860
P304
P3181
P356
10.1074/JBC.M003492200
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P577
2000-11-03T00:00:00Z