Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
about
Unbalanced replication as a major source of genetic instability in cancer cellsDevelopmental context determines latency of MYC-induced tumorigenesisExcessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphomaGrowth inhibition and apoptosis induced by daunomycin-conjugated triplex-forming oligonucleotides targeting the c-myc gene in prostate cancer cellsMYC-driven aggressive B-cell lymphomas: biology, entity, differential diagnosis and clinical managementMYC activation is a hallmark of cancer initiation and maintenancec-Myc accelerates S-phase and requires WRN to avoid replication stressExamination of the expanding pathways for the regulation of p21 expression and activity.A natural-like synthetic small molecule impairs bcr-abl signaling cascades and induces megakaryocyte differentiation in erythroleukemia cellsIntegrated network analysis reveals a novel role for the cell cycle in 2009 pandemic influenza virus-induced inflammation in macaque lungsSome Statistical Strategies for DAE-seq Data Analysis: Variable Selection and Modeling Dependencies among Observations.Deciphering c-MYC-regulated genes in two distinct tissues.In vivo-in vitro toxicogenomic comparison of TCDD-elicited gene expression in Hepa1c1c7 mouse hepatoma cells and C57BL/6 hepatic tissueOral squamous cell carcinoma proliferative phenotype is modulated by proanthocyanidins: a potential prevention and treatment alternative for oral cancerMYC prevents apoptosis and enhances endoreduplication induced by paclitaxel.Systematic screening of isogenic cancer cells identifies DUSP6 as context-specific synthetic lethal target in melanoma.Inactivation of MYC reverses tumorigenesis.c-myc and N-myc promote active stem cell metabolism and cycling as architects of the developing brain.Transformation of follicular lymphoma to diffuse large-cell lymphoma: alternative patterns with increased or decreased expression of c-myc and its regulated genes.BRCA1 and cell signaling.Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem CellsOverexpression of c-Myc alters G(1)/S arrest following ionizing radiationTherapeutic strategies to inhibit MYCActivated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation.Genetic regulators of large-scale transcriptional signatures in cancer.Akt and c-Myc induce stem-cell markers in mature primary p53⁻/⁻ astrocytes and render these cells gliomagenic in the brain of immunocompetent mice.Viral-mediated noisy gene expression reveals biphasic E2f1 response to MYCA conserved Myc protein domain, MBIV, regulates DNA binding, apoptosis, transformation, and G2 arrest.T-cadherin-mediated cell growth regulation involves G2 phase arrest and requires p21(CIP1/WAF1) expressionMyc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3.Defective double-strand DNA break repair and chromosomal translocations by MYC overexpression.Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivationHigh risk HPV types 18 and 16 are potent modulators of oral squamous cell carcinoma phenotypes in vitro.The Mechanism by Which MYCN Amplification Confers an Enhanced Sensitivity to a PCNA-Derived Cell Permeable Peptide in Neuroblastoma Cells.Cardiac myocyte cell cycle control in development, disease, and regeneration.Gene expression profiling in diffuse large B-cell lymphoma.E2F1 expression is deregulated and plays an oncogenic role in sporadic Burkitt's lymphoma.Copy number gain and oncogenic activity of YWHAZ/14-3-3zeta in head and neck squamous cell carcinoma.c-Myc induction of programmed cell death may contribute to carcinogenesis: a perspective inspired by several concepts of chemical carcinogenesis.Chromosome instability and deregulated proliferation: an unavoidable duo.
P2860
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P2860
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
description
2000 nî lūn-bûn
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2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年學術文章
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Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@ast
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@en
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@en-gb
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@nl
type
label
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@ast
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@en
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@en-gb
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@nl
prefLabel
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@ast
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@en
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@en-gb
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@nl
P2093
P2860
P921
P356
P1476
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts
@en
P2093
P2860
P304
P356
10.1073/PNAS.190327097
P407
P577
2000-09-12T00:00:00Z