WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain
about
Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calciumSodium-potassium ATPase 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stressThe E3 ligase Smurf1 regulates Wolfram syndrome protein stability at the endoplasmic reticulumWolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cellsWFS1 protein modulates the free Ca(2+) concentration in the endoplasmic reticulumGenome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biologyDeterminants of different deep and superficial CA1 pyramidal cell dynamics during sharp-wave ripples.Is there a relationship between Wolfram syndrome carrier status and suicide?Wolfram gene (WFS1) mutation causes autosomal dominant congenital nuclear cataract in humansWolfram syndrome: new mutations, different phenotypeWFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cellsExpression and localization of Wolfram syndrome 1 gene in the developing rat pancreasCalcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosisWolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretionCisd2 deficiency drives premature aging and causes mitochondria-mediated defects in miceNeuroimaging evidence of deficient axon myelination in Wolfram syndrome.A novel WFS1 mutation in a family with dominant low frequency sensorineural hearing loss with normal VEMP and EcochG findingsAutosomal dominant optic neuropathy and sensorineual hearing loss associated with a novel mutation of WFS1Mitochondrial metabolism and diabetesA novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions.Spontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A2 expression: a role for regulation by SREBP-1Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk.Wfs1 is expressed in dopaminoceptive regions of the amniote brain and modulates levels of D1-like receptors.Decreased insulin secretion and increased risk of type 2 diabetes associated with allelic variations of the WFS1 gene: the Data from Epidemiological Study on the Insulin Resistance Syndrome (DESIR) prospective study.Group VIA Ca2+-independent phospholipase A2 (iPLA2beta) and its role in beta-cell programmed cell death.Early brain vulnerability in Wolfram syndrome.The other, forgotten genome: mitochondrial DNA and mental disorders.Sideroblastic anaemias.Wolframin mutations and hospitalization for psychiatric illness.Non-syndromic autosomal-dominant deafness.Organelles do not colocalize with mRNA granules in post-ischemic neurons.Selective cognitive and psychiatric manifestations in Wolfram Syndrome.Molecular characterization of WFS1 in patients with Wolfram syndromeNuclear membrane diversity: underlying tissue-specific pathologies in disease?Prohormone convertase 2 activity is increased in the hippocampus of Wfs1 knockout mice.Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors.Probing the stress and depression circuits with a disease gene.Phenotype Prediction of Pathogenic Nonsynonymous Single Nucleotide Polymorphisms in WFS1A homozygous mutation in a novel zinc-finger protein, ERIS, is responsible for Wolfram syndrome 2Early presentation of gait impairment in Wolfram Syndrome.
P2860
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P2860
WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain
description
2001 nî lūn-bûn
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2001 թուականի Մարտին հրատարակուած գիտական յօդուած
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2001 թվականի մարտին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
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2001年論文
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2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
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2001年论文
@wuu
name
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@ast
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@en
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@en-gb
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@nl
type
label
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@ast
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@en
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@en-gb
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@nl
prefLabel
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@ast
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@en
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@en-gb
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@nl
P2093
P921
P3181
P356
P1476
WFS1 (Wolfram syndrome 1) gene ...... uronal expression in rat brain
@en
P2093
Y Matsuzaki
Y Tanizawa
Y Watanabe
P304
P3181
P356
10.1093/HMG/10.5.477
P407
P577
2001-03-01T00:00:00Z