Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
about
Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)A comprehensive glossary of autophagy-related molecules and processes (2nd edition)Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram SyndromeMutation of the His ligand in mitoNEET stabilizes the 2Fe–2S cluster despite conformational heterogeneity in the ligand environmentStructure and Molecular Evolution of CDGSH Iron-Sulfur DomainsA point mutation in the [2Fe–2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor propertiesNutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugsGenetic studies in Drosophila and humans support a model for the concerted function of CISD2, PPT1 and CLN3 in disease.A novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions.A critical role of Fas-associated protein with death domain phosphorylation in intracellular reactive oxygen species homeostasis and aging.The optic nerve: a "mito-window" on mitochondrial neurodegenerationA calcium-dependent protease as a potential therapeutic target for Wolfram syndromeFacile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor proteinThe Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer.Coanalysis of GWAS with eQTLs reveals disease-tissue associations.Dysregulation of Mitochondrial Functions and Osteogenic Differentiation in Cisd2-Deficient Murine Induced Pluripotent Stem CellsTAp73 depletion accelerates aging through metabolic dysregulationInteractions between mitoNEET and NAF-1 in cells.CISD2 associated with proliferation indicates negative prognosis in patients with hepatocellular carcinomaActivation of apoptosis in NAF-1-deficient human epithelial breast cancer cellsLoss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging.New insight into curcumin-based therapy in spinal cord injuries: CISD2 regulation.Overexpressed CISD2 has prognostic value in human gastric cancer and promotes gastric cancer cell proliferation and tumorigenesis via AKT signaling pathway.REGγ deficiency promotes premature aging via the casein kinase 1 pathway.NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth.Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasisRedox control of human mitochondrial outer membrane protein MitoNEET [2Fe-2S] clusters by biological thiols and hydrogen peroxide.Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates.Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1.Mitochondrial oxidative damage and apoptosis in age-related hearing loss.Negative regulation of autophagyWS1 gene mutation analysis of Wolfram syndrome in a Chinese patient and a systematic review of literatures.Nutrient availability links mitochondria, apoptosis, and obesity.Current status of auditory aging and anti-aging research.Cisd2 mediates lifespan: is there an interconnection among Ca²⁺ homeostasis, autophagy, and lifespan?Role of mitochondrial dysfunction and dysregulation of Ca(2+) homeostasis in insulin insensitivity of mammalian cells.Role of Endoplasmic Reticulum-Mitochondria Communication in Type 2 Diabetes.Mitochondrial remodeling: Rearranging, recycling, and reprogramming.CISD2 expression is a novel marker correlating with pelvic lymph node metastasis and prognosis in patients with early-stage cervical cancer.
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P2860
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
description
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
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im Mai 2009 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2009/05/15)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/05/15)
@nl
наукова стаття, опублікована в травні 2009
@uk
مقالة علمية (نشرت في 15-5-2009)
@ar
name
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
@ast
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
@en
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
@nl
type
label
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
@ast
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
@en
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
@nl
prefLabel
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
@ast
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
@en
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
@nl
P2093
P2860
P3181
P356
P1433
P1476
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice
@en
P2093
Cheng-Heng Kao
Chia-Yu Wu
Chih-Hao Wang
Ching-Yen Tsai
Chu-Wen Yang
Fu-Chin Liu
Ming-Ta Hsu
Shih-Feng Tsai
Ting-Fen Tsai
Ya-Ting Chen
P2860
P304
P3181
P356
10.1101/GAD.1779509
P577
2009-05-15T00:00:00Z