Very large G protein-coupled receptor-1, the largest known cell surface protein, is highly expressed in the developing central nervous system
about
The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1Mutations in the VLGR1 gene implicate G-protein signaling in the pathogenesis of Usher syndrome type IIA nonsense mutation of the MASS1 gene in a family with febrile and afebrile seizuresGenomewide pharmacogenomic study of metabolic side effects to antipsychotic drugsUsher syndrome: animal models, retinal function of Usher proteins, and prospects for gene therapyCa2+ regulation of ion transport in the Na+/Ca2+ exchangerA tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR133Sticky signaling--adhesion class G protein-coupled receptors take the stageThe Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC.A novel Usher protein network at the periciliary reloading point between molecular transport machineries in vertebrate photoreceptor cellsDREG, a developmentally regulated G protein-coupled receptor containing two conserved proteolytic cleavage sitesVlgr1 is required for proper stereocilia maturation of cochlear hair cellsThe very large G-protein-coupled receptor VLGR1: a component of the ankle link complex required for the normal development of auditory hair bundles.Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C.Usher syndrome: Hearing loss, retinal degeneration and associated abnormalities.Divalent counterions tether membrane-bound carbohydrates to promote the cohesion of auditory hair bundles.Function and expression pattern of nonsyndromic deafness genesDistinct expression and function of whirlin isoforms in the inner ear and retina: an insight into pathogenesis of USH2D and DFNB31.Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site (GPSBiochemical characterization of native Usher protein complexes from a vesicular subfraction of tracheal epithelial cells.A human pluripotent stem cell surface N-glycoproteome resource reveals markers, extracellular epitopes, and drug targets.Constitutive Gαi coupling activity of very large G protein-coupled receptor 1 (VLGR1) and its regulation by PDZD7 protein.A novel microdeletion syndrome involving 5q14.3-q15: clinical and molecular cytogenetic characterization of three patientsA profile of transcriptomic changes in the rd10 mouse model of retinitis pigmentosa.A large deletion in GPR98 causes type IIC Usher syndrome in male and female members of an Iranian family.Role for a novel Usher protein complex in hair cell synaptic maturation.Current understanding of usher syndrome type II.Importance of a N-terminal aspartate in the internalization of the neuropeptide Y Y2 receptor.CD133/CD140a-based isolation of distinct human multipotent neural progenitor cells and oligodendrocyte progenitor cellsHow and why do GPCRs dimerize?Schizophrenia and epilepsy: is there a shared susceptibility?The very large G protein coupled receptor (Vlgr1) in hair cells.Adhesion GPCR-Related Protein Networks.Adhesion GPCRs as a Putative Class of Metabotropic Mechanosensors.Biochemical Large-Scale Interaction Analysis of Murine Olfactory Receptors and Associated Signaling Proteins with Post-Synaptic Density 95, Drosophila Discs Large, Zona-Occludens 1 (PDZ) Domains.Deficiency of very large G-protein-coupled receptor-1 is a risk factor of tumor-related epilepsy: a whole transcriptome sequencing analysis.Genome-Wide Association Study to Find Modifiers for Tetralogy of Fallot in the 22q11.2 Deletion Syndrome Identifies Variants in the GPR98 Locus on 5q14.3.Macular cystoid spaces in patients with retinal dystrophy.Novel compound heterozygous mutations in the GPR98 (USH2C) gene identified by whole exome sequencing in a Moroccan deaf family.Scallop genome reveals molecular adaptations to semi-sessile life and neurotoxins.
P2860
Q24301988-F9C66299-8AFB-4BD3-BAAB-0A1C4C9DE9B0Q24306120-89ADBB62-DE16-48FB-8A82-89637D1892C5Q24313526-6DB980A2-3965-4FFF-B4BE-CC1F00998A5BQ24630309-12827A90-7EB8-4E81-B12A-B128E2EBD0C6Q24646440-D0313553-19C5-4E70-B31A-878A82A8A256Q26864939-0A2128C7-8A8E-4E40-9CDC-503EF4FBF628Q28119003-4E0A1AC5-1848-4BA1-8134-1BCD7276777DQ28291130-5F3963B7-CE63-4DA7-894C-69C9EBA5E65EQ28504635-657FBA26-C5C5-4261-A1A1-5FB59C6C4E97Q28510477-9F7CA53A-6BF8-4F66-B6F6-C7CC655CF508Q28513585-A4310E6B-4417-48C1-9353-970ECB0FEDDEQ28588493-2105063A-7534-4779-8858-E027B4C31FFAQ28589815-AA41E846-4FAA-4EF7-9FD0-D2C08FD19609Q28594174-8F6DEB1E-6902-429C-83CA-C2F75881E26BQ30389509-782C6162-DF71-4532-9D78-F9ACEBF0CFE9Q30463456-2003AE51-4DFA-4F28-B432-7571ECB9CC67Q30482629-8B2BBA8A-41DB-4517-8797-ACDB360C0A1EQ30667428-1BAA11AB-1689-421D-944A-7E91EC4894B8Q31110558-FE1DD5E8-9848-4811-B61C-63B2F38952FBQ33745351-4D5E7DE6-E6F6-47A3-8EF4-0387B2B459FAQ33949177-CFC38B6C-8343-4751-B473-744A8E96B8BEQ34107213-6FEEF38E-94EF-4D68-82AE-254CF60FFD2EQ34328088-F10C285E-3C33-4AC3-87D0-BBC95327C84DQ34529507-56F5391D-5902-4547-90A6-3746A27BA0DCQ35608563-483269CA-ACE2-47EF-ABFD-5A2B2B588AADQ35763614-DB68DFB1-812B-4872-BF3F-A21F0DDF2935Q35830124-DB8056D2-0130-43DE-9C09-C2B88203BAA7Q36963881-BD2EE90B-A2F1-4E45-AB05-675C87ACACABQ37025715-4146776F-B6AA-4E7B-A4E5-6A1A32C6C19BQ37120246-2A8C5571-CD63-4600-989E-96508945E118Q37401357-F6782579-6336-49CE-91F8-598ACA7F64E4Q38062457-9BCB1347-07B1-4942-A92D-A47F86AC492DQ39004694-D3E727A6-73B2-440D-A367-246646BC9EF7Q39004700-3039CF19-32CB-4BD8-8A69-0BBC2B4B8CA3Q39006035-68F8F326-B0DC-4FF8-B39F-EAD752A6DEFBQ41685604-604139BE-4559-4102-BDEA-3568A1466F17Q42678770-BCA95F76-31CC-426D-8C43-DAEEBDB68C54Q46499232-8571D10C-0552-4C88-A23E-CA6A93060513Q46809494-A931DC16-8048-4265-AD1E-9898CE588D99Q47122392-DC72C190-F845-4697-9215-190CFB530771
P2860
Very large G protein-coupled receptor-1, the largest known cell surface protein, is highly expressed in the developing central nervous system
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Very large G protein-coupled r ...... eloping central nervous system
@ast
Very large G protein-coupled r ...... eloping central nervous system
@en
Very large G protein-coupled r ...... eloping central nervous system
@en-gb
Very large G protein-coupled r ...... eloping central nervous system
@nl
type
label
Very large G protein-coupled r ...... eloping central nervous system
@ast
Very large G protein-coupled r ...... eloping central nervous system
@en
Very large G protein-coupled r ...... eloping central nervous system
@en-gb
Very large G protein-coupled r ...... eloping central nervous system
@nl
prefLabel
Very large G protein-coupled r ...... eloping central nervous system
@ast
Very large G protein-coupled r ...... eloping central nervous system
@en
Very large G protein-coupled r ...... eloping central nervous system
@en-gb
Very large G protein-coupled r ...... eloping central nervous system
@nl
P2093
P2860
P921
P356
P1476
Very large G protein-coupled r ...... eloping central nervous system
@en
P2093
D Randy McMillan
James A Richardson
Kathleen M Kayes-Wandover
Perrin C White
P2860
P304
P356
10.1074/JBC.M108929200
P407
P577
2002-01-04T00:00:00Z