A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR133
about
Model Organisms in G Protein-Coupled Receptor ResearchNew insights on Schwann cell developmentAdhesion G Protein-Coupled Receptors: From In Vitro Pharmacology to In Vivo MechanismsMutations of GPR126 are responsible for severe arthrogryposis multiplex congenitaThe adhesion GPCR GPR126 has distinct, domain-dependent functions in Schwann cell development mediated by interaction with laminin-211The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6Epithelial Gpr116 regulates pulmonary alveolar homeostasis via Gq/11 signaling.Adhesion GPCRs in Tumorigenesis.Oriented Cell Division in the C. elegans Embryo Is Coordinated by G-Protein Signaling Dependent on the Adhesion GPCR LAT-1.The Activation Mechanism of Glycoprotein Hormone Receptors with Implications in the Cause and Therapy of Endocrine DiseasesDihydromunduletone Is a Small-Molecule Selective Adhesion G Protein-Coupled Receptor AntagonistFunctional relevance of naturally occurring mutations in adhesion G protein-coupled receptor ADGRD1 (GPR133).Stalk-dependent and Stalk-independent Signaling by the Adhesion G Protein-coupled Receptors GPR56 (ADGRG1) and BAI1 (ADGRB1)The scales and tales of myelination: using zebrafish and mouse to study myelinating gliaSuper-complexes of adhesion GPCRs and neural guidance receptors.Myelinating glia differentiation is regulated by extracellular matrix elasticity.Gpr126/Adgrg6 Has Schwann Cell Autonomous and Nonautonomous Functions in Peripheral Nerve Injury and Repair.Disease-associated extracellular loop mutations in the adhesion G protein-coupled receptor G1 (ADGRG1; GPR56) differentially regulate downstream signaling.Activation of Adhesion GPCR EMR2/ADGRE2 Induces Macrophage Differentiation and Inflammatory Responses via Gα16/Akt/MAPK/NF-κB Signaling PathwaysTethered Agonism: A Common Activation Mechanism of Adhesion GPCRs.Classification, Nomenclature, and Structural Aspects of Adhesion GPCRs.G Protein-Coupled Receptors in Myelinating Glia.Proteinases, Their Extracellular Targets, and Inflammatory Signaling.Introduction: History of the Adhesion GPCR Field.7TM Domain Structure of Adhesion GPCRs.Understanding the Structural Basis of Adhesion GPCR Functions.Control of Adhesion GPCR Function Through Proteolytic Processing.Versatile Signaling Activity of Adhesion GPCRs.Adhesion GPCRs as a Putative Class of Metabotropic Mechanosensors.Adhesion GPCRs Govern Polarity of Epithelia and Cell Migration.Adhesion GPCRs as Novel Actors in Neural and Glial Cell Functions: From Synaptogenesis to Myelination.Adhesion G-protein coupled receptors and extracellular matrix proteins: Roles in myelination and glial cell development.GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth.Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity.Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains.Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons.Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4).Stachel-independent modulation of GPR56/ADGRG1 signaling by synthetic ligands directed to its extracellular region.Analysis of myelinated axon formation in zebrafish.How to wake a giant.
P2860
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P2860
A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR133
description
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2014
@ast
im Dezember 2014 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2014/12/24)
@sk
vědecký článek publikovaný v roce 2014
@cs
wetenschappelijk artikel (gepubliceerd op 2014/12/24)
@nl
наукова стаття, опублікована в грудні 2014
@uk
مقالة علمية (نشرت في 24-12-2014)
@ar
name
A tethered agonist within the ...... ed receptors GPR126 and GPR133
@ast
A tethered agonist within the ...... ed receptors GPR126 and GPR133
@en
A tethered agonist within the ...... ed receptors GPR126 and GPR133
@nl
type
label
A tethered agonist within the ...... ed receptors GPR126 and GPR133
@ast
A tethered agonist within the ...... ed receptors GPR126 and GPR133
@en
A tethered agonist within the ...... ed receptors GPR126 and GPR133
@nl
prefLabel
A tethered agonist within the ...... ed receptors GPR126 and GPR133
@ast
A tethered agonist within the ...... ed receptors GPR126 and GPR133
@en
A tethered agonist within the ...... ed receptors GPR126 and GPR133
@nl
P2093
P2860
P3181
P1433
P1476
A tethered agonist within the ...... ed receptors GPR126 and GPR133
@en
P2093
Amit Mogha
Julia Schön
Kay-Uwe Simon
Kelly R Monk
Liane Fischer
Lilian Marie Demberg
Maxi Cöster
Nina Auerbach
Sven Rothemund
Torsten Schöneberg
P2860
P304
P3181
P356
10.1016/J.CELREP.2014.11.036
P577
2014-12-18T00:00:00Z