Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules
about
Regulation of secreted Frizzled-related protein-1 by heparinQSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signalingNMR structure of the netrin-like domain (NTR) of human type I procollagen C-proteinase enhancer defines structural consensus of NTR domains and assesses potential proteinase inhibitory activity and ligand bindingSexually dimorphic expression of secreted frizzled-related (SFRP) genes in the developing mouse Müllerian ductMethylation and loss of Secreted Frizzled-Related Protein 3 enhances melanoma cell migration and invasionNovel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis.Determination of disulfide-bond linkages in proteins.Synergism between Wnt3a and heparin enhances osteogenesis via a phosphoinositide 3-kinase/Akt/RUNX2 pathway.Low resolution structure determination shows procollagen C-proteinase enhancer to be an elongated multidomain glycoprotein.Negative feedback regulation of Wnt signaling via N-linked fucosylation in zebrafish.Sfrp5 modulates both Wnt and BMP signaling and regulates gastrointestinal organogenesis [corrected] in the zebrafish, Danio rerio.Secreted Frizzled-related proteins: searching for relationships and patterns.sFRP-1 binds via its netrin-related motif to the N-module of thrombospondin-1 and blocks thrombospondin-1 stimulation of MDA-MB-231 breast carcinoma cell adhesion and migration.Neuroblast migration along the anteroposterior axis of C. elegans is controlled by opposing gradients of Wnts and a secreted Frizzled-related protein.Proliferation and pluripotency of human embryonic stem cells maintained on type I collagen.Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females.Secreted and transmembrane wnt inhibitors and activators.SFRP-4 abrogates Wnt-3a-induced beta-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiation.Secreted Wnt "inhibitors" are not just inhibitors: regulation of extracellular Wnt by secreted Frizzled-related proteins.The complex roles of Wnt antagonists in RCC.Secreted frizzled-related protein 4 and its implications in cancer and apoptosis.A pan-cancer analysis of secreted Frizzled-related proteins: re-examining their proposed tumour suppressive function.Matricellular proteins in cancer: a focus on secreted Frizzled-related proteins.The Netrin-related domain of Sfrp1 interacts with Wnt ligands and antagonizes their activity in the anterior neural plate.Secreted Frizzled-related Protein 2 (sFRP2) Redirects Non-canonical Wnt Signaling from Fz7 to Ror2 during Vertebrate Gastrulation.Repeated evolution of identical domain architecture in metazoan netrin domain-containing proteins.Sizzled is unique among secreted frizzled-related proteins for its ability to specifically inhibit bone morphogenetic protein-1 (BMP-1)/tolloid-like proteinases.Osteogenesis induced by frizzled-related protein (FRZB) is linked to the netrin-like domain.SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor.Mutations in the netrin-1 gene cause congenital mirror movements.A Role for Progesterone-Regulated sFRP4 Expression in Uterine Leiomyomas.The crystal structure of full-length Sizzled from Xenopus laevis yields insights into Wnt-antagonistic function of secreted Frizzled-related proteins.A novel gene's role in an ancient mechanism: secreted Frizzled-related protein 1 is a critical component in the anterior-posterior Wnt signaling network that governs the establishment of the anterior neuroectoderm in sea urchin embryos.Epigenetic silencing of sFRP1 activates the canonical Wnt pathway and contributes to increased cell growth and proliferation in hepatocellular carcinoma.
P2860
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P2860
Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modules
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Disulfide bond assignments of ...... ed homology and netrin modules
@ast
Disulfide bond assignments of ...... ed homology and netrin modules
@en
Disulfide bond assignments of ...... ed homology and netrin modules
@en-gb
Disulfide bond assignments of ...... ed homology and netrin modules
@nl
type
label
Disulfide bond assignments of ...... ed homology and netrin modules
@ast
Disulfide bond assignments of ...... ed homology and netrin modules
@en
Disulfide bond assignments of ...... ed homology and netrin modules
@en-gb
Disulfide bond assignments of ...... ed homology and netrin modules
@nl
prefLabel
Disulfide bond assignments of ...... ed homology and netrin modules
@ast
Disulfide bond assignments of ...... ed homology and netrin modules
@en
Disulfide bond assignments of ...... ed homology and netrin modules
@en-gb
Disulfide bond assignments of ...... ed homology and netrin modules
@nl
P2093
P2860
P356
P1476
Disulfide bond assignments of ...... ed homology and netrin modules
@en
P2093
Aykut Uren
David W Speicher
Jae Min Chong
Jeffrey S Rubin
P2860
P304
P356
10.1074/JBC.M108533200
P407
P577
2002-02-15T00:00:00Z