A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling
about
The role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancerThe Emerging and Diverse Roles of Src-Like Adaptor Proteins in Health and DiseaseRole of SRC-like adaptor protein (SLAP) in immune and malignant cell signaling.The Src-like adaptor protein 2 regulates colony-stimulating factor-1 receptor signaling and down-regulation.Cloning and characterization of human Src-like adaptor protein 2 and a novel splice isoform, SLAP-2-v.Normal T-cell development and immune functions in TRIM-deficient mice.SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice.Negative feedback of T cell activation through inhibitory adapters and costimulatory receptors.Src-like adaptor protein regulates osteoclast generation and survival.Mechanism of upregulation of the inhibitory regulator, src-like adaptor protein (SLAP), by glucocorticoids in mast cells.Src-like adaptor protein (SLAP) is upregulated in antigen-stimulated mast cells and acts as a negative regulator.Tyr-298 in ephrinB1 is critical for an interaction with the Grb4 adaptor protein.Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex.A potential role for the Src-like adapter protein SLAP-2 in signaling by the colony stimulating factor-1 receptor.
P2860
Q26770682-EB6A02F4-526B-4BA5-A261-CCA8621C94E8Q26785507-572AD1C0-717F-4D35-878A-AC53717427DCQ30009207-FB551F1F-B6FF-46A5-972D-7D73A65982C1Q30158029-55AAA67D-627C-4B38-A246-118D29198C48Q34170522-15C79E71-84EA-40A8-88C1-74ED4C8311EFQ34564794-07861FC1-9BEB-4345-B0EA-DF6C65FFE31DQ34802412-F0C58990-9278-4A6B-8CE3-630B7A5ED61CQ35096700-DCD3D6CC-3D96-4A2C-8EBC-DA801E78251BQ36922566-F2CBEEE4-416D-48D6-96FD-964838FEC066Q37131427-56AA0FF2-8CB0-4542-B738-71AA96E4077AQ37199195-47F2B458-DFF4-4D8B-8912-71B2818C92DAQ41972837-4087D06E-89A6-419C-B1AF-0332D141C05BQ46124218-A2C71DCF-1873-4920-AD69-A0E22B4F98EFQ54607589-FB192AC8-AC19-415C-A929-5B2DABC88C3E
P2860
A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@ast
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@en
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@en-gb
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@nl
type
label
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@ast
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@en
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@en-gb
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@nl
prefLabel
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@ast
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@en
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@en-gb
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@nl
P2093
P2860
P50
P921
P356
P1476
A novel Src homology 2 domain- ...... ates T cell receptor signaling
@en
P2093
Matthias Mann
Minerva M Fernandez
Nieves Ibarrola
Sansana Sawasdikosol
P2860
P304
P356
10.1074/JBC.M110318200
P407
P577
2002-05-24T00:00:00Z