Src-like adaptor protein (Slap) is a negative regulator of mitogenesis - sprookjes - yvandenbroek - TriplyDB

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

http://www.wikidata.org/entity/Q24314743

about

Functional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signaling A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling The adaptor protein Tom1L1 is a negative regulator of Src mitogenic signaling induced by growth factors Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domain SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling The role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancer The Emerging and Diverse Roles of Src-Like Adaptor Proteins in Health and Disease Role of SRC-like adaptor protein (SLAP) in immune and malignant cell signaling.SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2.The Src-like adaptor protein 2 regulates colony-stimulating factor-1 receptor signaling and down-regulation.Slap negatively regulates Src mitogenic function but does not revert Src-induced cell morphology changes.Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling Negative regulation of receptor tyrosine kinase signals.On-bead screening of combinatorial libraries: reduction of nonspecific binding by decreasing surface ligand density.Growth factor signaling pathways in vascular development.Src-Like adaptor protein (SLAP) binds to the receptor tyrosine kinase Flt3 and modulates receptor stability and downstream signaling.Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling.Src-like adaptor protein (SLAP) regulates B cell receptor levels in a c-Cbl-dependent manner.Src-like adaptor protein regulates osteoclast generation and survival.A susceptibility locus for papillary thyroid carcinoma on chromosome 8q24.Mechanism of upregulation of the inhibitory regulator, src-like adaptor protein (SLAP), by glucocorticoids in mast cells.siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation.Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor.The proto-oncogene c-Cbl is a negative regulator of DNA synthesis initiated by both receptor and cytoplasmic tyrosine kinases.The Tom1L1-clathrin heavy chain complex regulates membrane partitioning of the tyrosine kinase Src required for mitogenic and transforming activities.Cyclin E and cyclin A are likely targets of Src for PDGF-induced DNA synthesis in fibroblasts.The Src-like adaptor protein regulates PDGF-induced actin dorsal ruffles in a c-Cbl-dependent manner.c-Cbl-facilitated cytoskeletal effects in v-Abl-transformed fibroblasts are regulated by membrane association of c-Cbl.Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex.

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P2860

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

http://www.wikidata.org/entity/Q24314743

description

1998 nî lūn-bûn

@nan

1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի օգոստոսին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

@zh-hk

1998年論文

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1998年論文

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1998年论文

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name

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

@ast

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

@en

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

@en-gb

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

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type

label

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

@ast

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

@en

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

@en-gb

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

@nl

prefLabel

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

@ast

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

@en

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

@en-gb

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

@nl

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S0960-9822(98)70400-2

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Current Biology

P1476

Src-like adaptor protein (Slap) is a negative regulator of mitogenesis

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P2093

A Kazlauskas

http://www.w3.org/2001/XMLSchema#string

A Pandey

http://www.w3.org/2001/XMLSchema#string

G Alonso

http://www.w3.org/2001/XMLSchema#string

S A Courtneidge

http://www.w3.org/2001/XMLSchema#string

S Roche

http://www.w3.org/2001/XMLSchema#string

V M Dixit

http://www.w3.org/2001/XMLSchema#string

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975-8

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scholarly article

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4455374

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10.1016/S0960-9822(98)70400-2

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P433

17

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8

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1998-08-27T00:00:00Z

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9742401

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