Identification of a switch in neurotrophin signaling by selective tyrosine phosphorylation
about
Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowthKidins220/ARMS is transported by a kinesin-1-based mechanism likely to be involved in neuronal differentiationNeurotrophin-regulated signalling pathwaysStepping Out of the Shade: Control of Neuronal Activity by the Scaffold Protein Kidins220/ARMSThe long coiled-coil protein NECC2 is associated to caveolae and modulates NGF/TrkA signaling in PC12 cells [corrected]Ankyrin Repeat-rich Membrane Spanning/Kidins220 protein regulates dendritic branching and spine stability in vivoA dynamic view of domain-motif interactions.Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transportA neuron-specific cytoplasmic dynein isoform preferentially transports TrkB signaling endosomesTrk-signaling endosomes are generated by Rac-dependent macroendocytosis.The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42Kidins220/ARMS modulates the activity of microtubule-regulating proteins and controls neuronal polarity and developmentTC-PTP dephosphorylates the guanine nucleotide exchange factor C3G (RapGEF1) and negatively regulates differentiation of human neuroblastoma cells.The ARMS/Kidins220 scaffold protein modulates synaptic transmission.Upregulated ankyrin repeat-rich membrane spanning protein contributes to tumour progression in cutaneous melanomaAnkyrin repeat-rich membrane spanning (ARMS)/Kidins220 scaffold protein regulates neuroblastoma cell proliferation through p21.A selective role for ARMS/Kidins220 scaffold protein in spatial memory and trophic support of entorhinal and frontal cortical neuronsNeuroplasticity underlying the comorbidity of pain and depressionProtein kinase D promotes plasticity-induced F-actin stabilization in dendritic spines and regulates memory formation.PKD1, PKD2, and their substrate Kidins220 regulate neurotensin secretion in the BON human endocrine cell line.Prediction of functional phosphorylation sites by incorporating evolutionary informationRole of the brain-derived neurotrophic factor at glutamatergic synapses.Cellular and molecular mechanisms regulating neuronal growth by brain-derived neurotrophic factor.Crosstalk of cell polarity signaling pathways.Ankyrin-rich membrane spanning protein plays a critical role in nuclear factor-kappa B signaling.Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity.Development of a neuroprotective peptide that preserves survival pathways by preventing Kidins220/ARMS calpain processing induced by excitotoxicityKidins220 and tumour development: Insights into a complexity of cross-talk among signalling pathways (Review).Functions of the multi-interacting protein KIDINS220/ARMS in cancer and other pathologies.Ph-like acute lymphoblastic leukemia with a novel PAX5-KIDINS220 fusion transcript.ARMS is phosphorylated by active TrkA receptorCrk's SH3 domain engages C3GC3G stimulates nucleotide exchange on Rap1Targeting NMDA receptors in stroke: new hope in neuroprotection.
P2860
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P2860
Identification of a switch in neurotrophin signaling by selective tyrosine phosphorylation
description
2006 nî lūn-bûn
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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Identification of a switch in ...... ctive tyrosine phosphorylation
@ast
Identification of a switch in ...... ctive tyrosine phosphorylation
@en
Identification of a switch in ...... ctive tyrosine phosphorylation
@en-gb
Identification of a switch in ...... ctive tyrosine phosphorylation
@nl
type
label
Identification of a switch in ...... ctive tyrosine phosphorylation
@ast
Identification of a switch in ...... ctive tyrosine phosphorylation
@en
Identification of a switch in ...... ctive tyrosine phosphorylation
@en-gb
Identification of a switch in ...... ctive tyrosine phosphorylation
@nl
prefLabel
Identification of a switch in ...... ctive tyrosine phosphorylation
@ast
Identification of a switch in ...... ctive tyrosine phosphorylation
@en
Identification of a switch in ...... ctive tyrosine phosphorylation
@en-gb
Identification of a switch in ...... ctive tyrosine phosphorylation
@nl
P2860
P50
P356
P1476
Identification of a switch in ...... ctive tyrosine phosphorylation
@en
P2093
Hiroko Yano
P2860
P304
P356
10.1074/JBC.M504163200
P407
P577
2006-01-13T00:00:00Z