A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein
about
Identification of a switch in neurotrophin signaling by selective tyrosine phosphorylationRap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowthKidins220/ARMS is transported by a kinesin-1-based mechanism likely to be involved in neuronal differentiationNeurotrophin-regulated signalling pathwaysStepping Out of the Shade: Control of Neuronal Activity by the Scaffold Protein Kidins220/ARMSThe long coiled-coil protein NECC2 is associated to caveolae and modulates NGF/TrkA signaling in PC12 cells [corrected]Src-dependent TrkA transactivation is required for pituitary adenylate cyclase-activating polypeptide 38-mediated Rit activation and neuronal differentiationRap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activationAnkyrin Repeat-rich Membrane Spanning/Kidins220 protein regulates dendritic branching and spine stability in vivoIn vivo regulation of NGF-mediated functions by Nedd4-2 ubiquitination of TrkAThe neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42Kidins220/ARMS modulates the activity of microtubule-regulating proteins and controls neuronal polarity and developmentRetrograde neurotrophic signaling requires a protein interacting with receptor tyrosine kinases via C2H2 zinc fingers.Cardiovascular actions of neurotrophinsThe ARMS/Kidins220 scaffold protein modulates synaptic transmission.Kidins220/ARMS is a novel modulator of short-term synaptic plasticity in hippocampal GABAergic neuronsThe ankyrin repeat-rich membrane spanning (ARMS)/Kidins220 scaffold protein is regulated by activity-dependent calpain proteolysis and modulates synaptic plasticity.Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation.Upregulated ankyrin repeat-rich membrane spanning protein contributes to tumour progression in cutaneous melanomaAnkyrin repeat-rich membrane spanning (ARMS)/Kidins220 scaffold protein regulates neuroblastoma cell proliferation through p21.A selective role for ARMS/Kidins220 scaffold protein in spatial memory and trophic support of entorhinal and frontal cortical neuronsNovel Kidins220/ARMS Splice Isoforms: Potential Specific Regulators of Neuronal and Cardiovascular Development.Rare variants in the neurotrophin signaling pathway implicated in schizophrenia risk.{alpha}-Syntrophin regulates ARMS localization at the neuromuscular junction and enhances EphA4 signaling in an ARMS-dependent manner.PKD1, PKD2, and their substrate Kidins220 regulate neurotensin secretion in the BON human endocrine cell line.Phenotypically distinct subtypes of psychosis accompany novel or rare variants in four different signaling genes.Prefrontal neuronal integrity predicts symptoms and cognition in schizophrenia and is sensitive to genetic heterogeneity.Blockade of ankyrin repeat-rich membrane spanning protein modulates extracellular signal-regulated kinase expression and inhibits allergic inflammation in ovalbumin-sensitized mice.Neurotrophin signalling: novel insights into mechanisms and pathophysiology.Kidins220/ARMS is expressed in neuroblastoma tumors and stabilizes neurotrophic signaling in a human neuroblastoma cell line.The Trk A, B, C's of neurotrophins in the cochlea.TrkB receptor signalling: implications in neurodegenerative, psychiatric and proliferative disorders.The entorhinal cortex and neurotrophin signaling in Alzheimer's disease and other disorders.Dopamine D1 receptor-induced signaling through TrkB receptors in striatal neurons.Ankyrin-rich membrane spanning protein as a novel modulator of transient receptor potential vanilloid 1-function in nociceptive neurons.Neurotrophin Signaling and Stem Cells-Implications for Neurodegenerative Diseases and Stem Cell Therapy.Integral Characterization of Defective BDNF/TrkB Signalling in Neurological and Psychiatric Disorders Leads the Way to New Therapies.Kidins220/ARMS is an essential modulator of cardiovascular and nervous system development.Ankyrin-rich membrane spanning protein plays a critical role in nuclear factor-kappa B signaling.Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems.
P2860
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P2860
A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein
description
2004 nî lūn-bûn
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2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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name
A unique pathway for sustained ...... rich membrane-spanning protein
@ast
A unique pathway for sustained ...... rich membrane-spanning protein
@en
A unique pathway for sustained ...... rich membrane-spanning protein
@nl
type
label
A unique pathway for sustained ...... rich membrane-spanning protein
@ast
A unique pathway for sustained ...... rich membrane-spanning protein
@en
A unique pathway for sustained ...... rich membrane-spanning protein
@nl
prefLabel
A unique pathway for sustained ...... rich membrane-spanning protein
@ast
A unique pathway for sustained ...... rich membrane-spanning protein
@en
A unique pathway for sustained ...... rich membrane-spanning protein
@nl
P2860
P50
P356
P1433
P1476
A unique pathway for sustained ...... rich membrane-spanning protein
@en
P2093
Hiroko Yano
P2860
P304
P356
10.1038/SJ.EMBOJ.7600253
P407
P577
2004-06-16T00:00:00Z