An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
about
Identification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A4 hydrolaseRegulation of the human leukocyte-derived arginine aminopeptidase/endoplasmic reticulum-aminopeptidase 2 gene by interferon-gammaAssociation scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variantsEndoplasmic reticulum aminopeptidase-1 functions regulate key aspects of the innate immune responseCrystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimmingFrom HLA-B27 to spondyloarthritis: a journey through the ER.Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association studyInteraction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility.Epistatic interaction of ERAP1 and HLA-B in Behçet disease: a replication study in the Spanish populationAn overview of genetics of paediatric rheumatic diseases.A role for naturally occurring alleles of endoplasmic reticulum aminopeptidases in tumor immunity and cancer pre-disposition.Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer.Molecular and cellular mechanisms of ectodomain sheddingIn vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib moleculesERAP1 genetic variations associated with HLA-B27 interaction and disease severity of syndesmophytes formation in Taiwanese ankylosing spondylitis.Complexity, contradictions, and conundrums: studying post-proteasomal proteolysis in HLA class I antigen presentation.Genetic association with ERAP1 in psoriasis is confined to disease onset after puberty and not dependent on HLA-C*06.Ankylosing spondylitis: from cells to genesPeptides: the cornerstone of HLA-B27 biology and pathogenetic role in spondyloarthritis.HLA-B27 misfolding and spondyloarthropathies.Investigating the genetic association between ERAP1 and ankylosing spondylitis.Genetics of rheumatic disease.Post-proteasomal and proteasome-independent generation of MHC class I ligands.Endoplasmic reticulum aminopeptidase 1 and interleukin-23 receptor in ankylosing spondylitis.ERAP1 in the pathogenesis of ankylosing spondylitis.Endoplasmic reticulum aminopeptidases in the pathogenesis of ankylosing spondylitis.Substrate-dependent nitric oxide synthesis by secreted endoplasmic reticulum aminopeptidase 1 in macrophages.Differences between disease-associated endoplasmic reticulum aminopeptidase 1 (ERAP1) isoforms in cellular expression, interactions with tumour necrosis factor receptor 1 (TNF-R1) and regulation by cytokines.Functional Genomics and Its Bench-to-Bedside Translation Pertaining to the Identified Susceptibility Alleles and Loci in Ankylosing Spondylitis.Secretion of endoplasmic reticulum aminopeptidase 1 is involved in the activation of macrophages induced by lipopolysaccharide and interferon-gammaThiol isomerases negatively regulate the cellular shedding activity of ADAM17.The influence of ERAP1 gene variants on clinical phenotype in ankylosing spondylitis.ERAP1 Gene Expression Is Influenced by Nonsynonymous Polymorphisms Associated With Predisposition to Spondyloarthritis.Association of ERAP1 Allelic Variants with Risk of Ankylosing SpondylitisMorphine-mediated alteration of hypertension-related gene expression in human white blood cells and multilineage progenitor cells.The association between seven ERAP1 polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis involving 8,530 cases and 12,449 controls.Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease.Radiographic severity of ankylosing spondylitis is associated with polymorphism of the large multifunctional peptidase 2 gene in the Spondyloarthritis Research Consortium of Canada cohort.Reduced activity of the hypertension-associated Lys528Arg mutant of human adipocyte-derived leucine aminopeptidase (A-LAP)/ER-aminopeptidase-1.Functional variants of ERAP1 gene are associated with HLA-B27 positive spondyloarthritis.
P2860
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P2860
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@ast
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@en
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@en-gb
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@nl
type
label
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@ast
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@en
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@en-gb
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@nl
prefLabel
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@ast
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@en
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@en-gb
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@nl
P2093
P2860
P921
P356
P1476
An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
@en
P2093
Farshid N Rouhani
Feras Hawari
Stewart J Levine
P2860
P304
P356
10.1074/JBC.M300456200
P407
P577
2003-08-01T00:00:00Z