Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells
about
CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnoverDishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1.KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progressionMyocilin, a glaucoma-associated protein, promotes cell migration through activation of integrin-focal adhesion kinase-serine/threonine kinase signaling pathwayCell polarity signaling in the plasticity of cancer cell invasivenessTargeting and transport: how microtubules control focal adhesion dynamicsNon-canonical WNT signalling in the lungHuman embryonic stem cell-derived cardiomyocytes migrate in response to gradients of fibronectin and Wnt5aAn AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential.Wnt5a is strongly expressed at the leading edge in non-melanoma skin cancer, forming active gradients, while canonical Wnt signalling is repressed.Planar cell polarity aligns osteoblast division in response to substrate strainShroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure.Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively.Silencing of Wnt5a during colon cancer metastasis involves histone modifications.Wnt-frizzled signaling is part of an FGF-induced cascade that promotes lens fiber differentiation.The importance of foetal movement for co-ordinated cartilage and bone development in utero : clinical consequences and potential for therapy.Multifaceted signaling regulators of chondrogenesis: Implications in cartilage regeneration and tissue engineeringUpregulation of the expression of Wnt5a promotes the proliferation of pancreatic cancer cells in vitro and in a nude mouse modelA mutation in FRIZZLED2 impairs Wnt signaling and causes autosomal dominant omodysplasiaLoss of adenomatous poliposis coli-α3 integrin interaction promotes endothelial apoptosis in mice and humans.Wnt5a signaling promotes apical and basolateral polarization of single epithelial cells.Wnt5b-associated exosomes promote cancer cell migration and proliferation.Filamin A interacting protein 1-like inhibits WNT signaling and MMP expression to suppress cancer cell invasion and metastasis.When pathways collide: collaboration and connivance among signalling proteins in development.Wnt5a: its signalling, functions and implication in diseases.Shaping microtubules into diverse patterns: molecular connections for setting up both ends.The tangled web of non-canonical Wnt signalling in neural migration.Ryk is essential for Wnt-5a-dependent invasiveness in human glioma.CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of β-catenin in carcinoma cellsWnt5a promotes human colon cancer cell migration and invasion but does not augment intestinal tumorigenesis in Apc1638N mice.Wnt5a inhibits the CpG oligodeoxynucleotide-triggered activation of human plasmacytoid dendritic cells.Wnt5b regulates mesenchymal cell aggregation and chondrocyte differentiation through the planar cell polarity pathway.Adenomatous polyposis coli nucleates actin assembly to drive cell migration and microtubule-induced focal adhesion turnover.Arl4c expression in colorectal and lung cancers promotes tumorigenesis and may represent a novel therapeutic target.
P2860
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P2860
Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Binding of APC and dishevelled ...... on dynamics in migrating cells
@ast
Binding of APC and dishevelled ...... on dynamics in migrating cells
@en
Binding of APC and dishevelled ...... on dynamics in migrating cells
@en-gb
Binding of APC and dishevelled ...... on dynamics in migrating cells
@nl
type
label
Binding of APC and dishevelled ...... on dynamics in migrating cells
@ast
Binding of APC and dishevelled ...... on dynamics in migrating cells
@en
Binding of APC and dishevelled ...... on dynamics in migrating cells
@en-gb
Binding of APC and dishevelled ...... on dynamics in migrating cells
@nl
prefLabel
Binding of APC and dishevelled ...... on dynamics in migrating cells
@ast
Binding of APC and dishevelled ...... on dynamics in migrating cells
@en
Binding of APC and dishevelled ...... on dynamics in migrating cells
@en-gb
Binding of APC and dishevelled ...... on dynamics in migrating cells
@nl
P2093
P2860
P356
P1433
P1476
Binding of APC and dishevelled ...... on dynamics in migrating cells
@en
P2093
Akira Kikuchi
Katsumi Fumoto
Shinji Matsumoto
Tetsuji Okamoto
P2860
P304
P356
10.1038/EMBOJ.2010.26
P407
P577
2010-04-07T00:00:00Z