about
Genealogy of an ancient protein family: the Sirtuins, a family of disordered membersSIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolismHDAC3 is negatively regulated by the nuclear protein DBC1Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signalingGenetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE studyEmerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disordersChromatin versus pathogens: the function of epigenetics in plant immunityProtective effects and mechanisms of sirtuins in the nervous systemObesity pharmacotherapy: current perspectives and future directionsTargeting sirtuin 1 to improve metabolism: all you need is NAD(+)?NAD+ as a signaling molecule modulating metabolismTrials with 'epigenetic' drugs: an updateRedox regulation of SIRT1 in inflammation and cellular senescenceThe Bicyclic Intermediate Structure Provides Insights into the Desuccinylation Mechanism of Human Sirtuin 5 (SIRT5)Stealing the Keys to the Kitchen: Viral Manipulation of the Host Cell Metabolic NetworkAntidicer RNAse activity of monocyte chemotactic protein-induced protein-1 is critical for inducing angiogenesisReactive oxygen species, cellular redox systems, and apoptosisSirT1 regulates energy metabolism and response to caloric restriction in mice.The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growthHuman sirt-1: molecular modeling and structure-function relationships of an unordered protein.Intake of red wine in different meals modulates oxidized LDL level, oxidative and inflammatory gene expression in healthy people: a randomized crossover trial.SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivitySynthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling.Cellular bioenergetics as a target for obesity therapy.Macrophage alpha1 AMP-activated protein kinase (alpha1AMPK) antagonizes fatty acid-induced inflammation through SIRT1Respected Sir(2): magic target for diabetesMaternal obesity during gestation impairs fatty acid oxidation and mitochondrial SIRT3 expression in rat offspring at weaningArabidopsis putative deacetylase AtSRT2 regulates basal defense by suppressing PAD4, EDS5 and SID2 expression.Brown fat as a therapy for obesity and diabetes.SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis.Aberrant cytoplasm localization and protein stability of SIRT1 is regulated by PI3K/IGF-1R signaling in human cancer cells.High-fat and obesogenic diets: current and future strategies to fight obesity and diabetes.Creation of an HDAC-based yeast screening method for evaluation of marine-derived actinomycetes: discovery of streptosetin A.High glucose induced alteration of SIRTs in endothelial cells causes rapid aging in a p300 and FOXO regulated pathway.Use of epigenetic drugs in disease: an overview.Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasisThe effects of NAD+ on apoptotic neuronal death and mitochondrial biogenesis and function after glutamate excitotoxicity.Regulation of FXR transcriptional activity in health and disease: Emerging roles of FXR cofactors and post-translational modificationsResveratrol in mammals: effects on aging biomarkers, age-related diseases, and life span.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Sirtuin functions in health and disease
@ast
Sirtuin functions in health and disease
@en
Sirtuin functions in health and disease
@nl
type
label
Sirtuin functions in health and disease
@ast
Sirtuin functions in health and disease
@en
Sirtuin functions in health and disease
@nl
prefLabel
Sirtuin functions in health and disease
@ast
Sirtuin functions in health and disease
@en
Sirtuin functions in health and disease
@nl
P921
P3181
P356
P1476
Sirtuin functions in health and disease
@en
P2093
Hiroyasu Yamamoto
P304
P3181
P356
10.1210/ME.2007-0079
P407
P577
2007-08-01T00:00:00Z