Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats
about
Structural basis for recruitment of BRCA2 by PALB2The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51Homologous recombination in DNA repair and DNA damage toleranceTrypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombinationInteraction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteinsUnraveling the mechanism of BRCA2 in homologous recombinationThe consequences of Rad51 overexpression for normal and tumor cellsMitotic homologous recombination maintains genomic stability and suppresses tumorigenesisReconstitution of DNA strand exchange mediated by Rhp51 recombinase and two mediatorsInterrogation of the protein-protein interactions between human BRCA2 BRC repeats and RAD51 reveals atomistic determinants of affinityHomologs of breast cancer genes in plantsFanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction.Real-time assembly and disassembly of human RAD51 filaments on individual DNA moleculesEffect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques.Contributions of the RAD51 N-terminal domain to BRCA2-RAD51 interaction.Drosophila brca2 is required for mitotic and meiotic DNA repair and efficient activation of the meiotic recombination checkpointCellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C.Characterization of a temperature-sensitive vertebrate clathrin heavy chain mutant as a tool to study clathrin-dependent events in vivoAssociation between the BRCA2 rs144848 polymorphism and cancer susceptibility: a meta-analysis.Comprehensive genomic analysis of a BRCA2 deficient human pancreatic cancerDeletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forksPlasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.Differing clinical impact of BRCA1 and BRCA2 mutations in serous ovarian cancer.Visualization and quantification of nascent RAD51 filament formation at single-monomer resolution.Association of BRCA2 N372H polymorphism with cancer susceptibility: a comprehensive review and meta-analysis.Arabidopsis BRCA2 and RAD51 proteins are specifically involved in defense gene transcription during plant immune responses.DNA damage and repair in endometrial cancer in correlation with the hOGG1 and RAD51 genes polymorphism.Missense variants of uncertain significance (VUS) altering the phosphorylation patterns of BRCA1 and BRCA2.Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms.Targeting lung cancer through inhibition of checkpoint kinases.A new assay for functional screening of BRCA2 linker region mutations identifies variants that alter chemoresistance to cisplatin.Homologous recombination and its regulationInfluence of Human p53 on Plant Development.Safeguarding genome stability: RASSF1A tumor suppressor regulates BRCA2 at stalled forks.D-loop formation by Brh2 protein of Ustilago maydis.Trypanosoma brucei BRCA2 acts in a life cycle-specific genome stability process and dictates BRC repeat number-dependent RAD51 subnuclear dynamics.Rad51 gain-of-function mutants that exhibit high affinity DNA binding cause DNA damage sensitivity in the absence of Srs2.Quality control of DNA break metabolism: in the 'end', it's a good thing.DNA-binding Domain within the Brh2 N Terminus Is the Primary Interaction Site for Association with DNA.
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P2860
Interaction with the BRCA2 C terminus protects RAD51-DNA filaments from disassembly by BRC repeats
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@ast
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@en
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@en-gb
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@nl
type
label
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@ast
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@en
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@en-gb
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@nl
prefLabel
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@ast
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@en
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@en-gb
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@nl
P2860
P921
P3181
P356
P1476
Interaction with the BRCA2 C t ...... rom disassembly by BRC repeats
@en
P2093
Luca Pellegrini
P2860
P2888
P304
P3181
P356
10.1038/NSMB1251
P407
P577
2007-06-01T00:00:00Z
P5875
P6179
1046238644