Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis
about
Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37E2 enzymes: more than just middle menAmino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8)Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection functionThe membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9E3 ligase FLRF (Rnf41) regulates differentiation of hematopoietic progenitors by governing steady-state levels of cytokine and retinoic acid receptorsAn E3 ubiquitin ligase, Really Interesting New Gene (RING) Finger 41, is a candidate gene for anxiety-like behavior and beta-carboline-induced seizuresThe Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic developmentThe E3 ubiquitin ligase neuregulin receptor degradation protein 1 (Nrdp1) promotes M2 macrophage polarization by ubiquitinating and activating transcription factor CCAAT/enhancer-binding Protein β (C/EBPβ)BRUCE, a giant E2/E3 ubiquitin ligase and inhibitor of apoptosis protein of the trans-Golgi network, is required for normal placenta development and mouse survivalThe ER structural protein Rtn4A stabilizes and enhances signaling through the receptor tyrosine kinase ErbB3alpha-Endosulfine is a conserved protein required for oocyte meiotic maturation in DrosophilaInducing death in tumor cells: roles of the inhibitor of apoptosis proteins.Overexpression of Nrdp1 in the heart exacerbates doxorubicin-induced cardiac dysfunction in miceBIRC6 protein, an inhibitor of apoptosis: role in survival of human prostate cancer cellsGene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type miceBRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1.Overexpression of BIRC6 Is a Predictor of Prognosis for Colorectal Cancer.Transcription of Nrdp1 by the androgen receptor is regulated by nuclear filamin A in prostate cancerKnockdown of the Inhibitor of Apoptosis BRUCE Sensitizes Resistant Breast Cancer Cells to Chemotherapeutic AgentsRole of Apollon in human melanoma resistance to antitumor agents that activate the intrinsic or the extrinsic apoptosis pathwaysRNF41 interacts with the VPS52 subunit of the GARP and EARP complexesThe retinoic acid derivative, ABPN, inhibits pancreatic cancer through induction of Nrdp1Systems analysis reveals down-regulation of a network of pro-survival miRNAs drives the apoptotic response in dilated cardiomyopathy.Suppressive Effect of Constructed shRNAs against Apollon Induces Apoptosis and Growth Inhibition in the HeLa Cell Line.Nrdp1-mediated degradation of BRUCE decreases cell viability and induces apoptosis in human 786-O renal cell carcinoma cellsApollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activationProtein partners of deubiquitinating enzymes.Ubiquitin at the crossroad of cell death and survival.Phosphorylation of the E3 ubiquitin ligase RNF41 by the kinase Par-1b is required for epithelial cell polarity.Oligomerization of the Nrdp1 E3 ubiquitin ligase is necessary for efficient autoubiquitination but not ErbB3 ubiquitination.Murine cytomegalovirus infection and apoptosis in organotypic retinal cultures.HILAQ: A Novel Strategy for Newly Synthesized Protein Quantification.The BIRC6 gene as a novel target for therapy of prostate cancer: dual targeting of inhibitors of apoptosis.Selenium mediated arsenic toxicity modifies cytotoxicity, reactive oxygen species and phosphorylated proteins.RNF41 (Nrdp1) controls type 1 cytokine receptor degradation and ectodomain shedding.7a protein of severe acute respiratory syndrome coronavirus inhibits cellular protein synthesis and activates p38 mitogen-activated protein kinase.Expression and clinical significance of Apollon in renal carcinoma.Expression and clinical significance of Apollon in esophageal squamous cell carcinoma.
P2860
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P2860
Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Nrdp1-mediated degradation of ...... thway for triggering apoptosis
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Nrdp1-mediated degradation of ...... thway for triggering apoptosis
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Nrdp1-mediated degradation of ...... thway for triggering apoptosis
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Nrdp1-mediated degradation of ...... thway for triggering apoptosis
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Nrdp1-mediated degradation of ...... thway for triggering apoptosis
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Nrdp1-mediated degradation of ...... thway for triggering apoptosis
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Nrdp1-mediated degradation of ...... thway for triggering apoptosis
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Nrdp1-mediated degradation of ...... thway for triggering apoptosis
@ast
Nrdp1-mediated degradation of ...... thway for triggering apoptosis
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Nrdp1-mediated degradation of ...... thway for triggering apoptosis
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P2093
P2860
P921
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P356
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Nrdp1-mediated degradation of ...... thway for triggering apoptosis
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P2093
Alfred L Goldberg
Junying Yuan
Shirley L Markant
Xiao-Bo Qiu
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7600075
P407
P577
2004-02-25T00:00:00Z