Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
about
Identification of a novel protein kinase Cδ-Smac complex that dissociates during paclitaxel-induced cell deathLivin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathwayCaspase-resistant Golgin-160 disrupts apoptosis induced by secretory pathway stress and ligation of death receptorsStructures of BIR domains from human NAIP and cIAP2Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the familyUbiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of HomeostasisRegulation of Cell Death by IAPs and Their AntagonistsInhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammationSmall molecules destabilize cIAP1 by activating auto-ubiquitylationThe membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic developmentCell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunitiesApollon/Bruce is upregulated by Humanin.A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila.Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins.The role of E3 ligases in the ubiquitin-dependent regulation of spermatogenesisMonomerization of cytosolic mature smac attenuates interaction with IAPs and potentiation of caspase activationOvercoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)Association of a polymorphism in the BIRC6 gene with pseudoexfoliative glaucoma.cIAP1 cooperatively inhibits procaspase-3 activation by the caspase-9 apoptosomeIdentification of BIRC6 as a novel intervention target for neuroblastoma therapy.Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma.Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases.XIAP impairs Smac release from the mitochondria during apoptosis.BIRC6 protein, an inhibitor of apoptosis: role in survival of human prostate cancer cellsγ-Synuclein antibodies have neuroprotective potential on neuroretinal cells via proteins of the mitochondrial apoptosis pathway.BRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1.The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukaemia and significantly increases the efficacy of nilotinibDrosophila BRUCE inhibits apoptosis through non-lysine ubiquitination of the IAP-antagonist REAPER.Knockdown of the Inhibitor of Apoptosis BRUCE Sensitizes Resistant Breast Cancer Cells to Chemotherapeutic AgentsProteasome inhibitors prevent cell death and prolong survival of mice challenged by Shiga toxin.Molecular characterization of protein kinase C delta (PKCδ)-Smac interactions.Role of Apollon in human melanoma resistance to antitumor agents that activate the intrinsic or the extrinsic apoptosis pathwaysConvergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells.In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs).BIRC6 mediates imatinib resistance independently of Mcl-1.BIRC6 (APOLLON) is down-regulated in acute myeloid leukemia and its knockdown attenuates neutrophil differentiation.Maternal Modifiers and Parent-of-Origin Bias of the Autism-Associated 16p11.2 CNV.Biology of mitochondria in neurodegenerative diseases.Accumulation of p53 via down-regulation of UBE2D family genes is a critical pathway for cadmium-induced renal toxicity
P2860
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P2860
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
@ast
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
@en
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
@nl
type
label
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
@ast
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
@en
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
@nl
prefLabel
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
@ast
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
@en
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
@nl
P2093
P2860
P3181
P356
P1433
P1476
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
@en
P2093
Atsushi Kawabata
Chizuko Hashimoto
Hirokazu Ohata
Hitoshi Nakamura
Keiko Sekine
Mikihiko Naito
Takashi Tsuruo
Tetsuo Noda
Toshiyasu Ishioka
Xiaodong Zhang
P2860
P2888
P304
P3181
P356
10.1038/NCB1159
P407
P577
2004-08-08T00:00:00Z
P5875
P6179
1008296844