Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit - sprookjes - yvandenbroek - TriplyDB

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

http://www.wikidata.org/entity/Q24307555

about

GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor In vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinase Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo Mutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts Molecular mechanism for a role of SHP2 in epidermal growth factor receptor signaling Phosphorylation sites at the C-terminus of the platelet-derived growth factor receptor bind phospholipase C gamma 1 Src family kinases are required for integrin but not PDGFR signal transduction.Bovine papillomavirus E5 protein induces oligomerization and trans-phosphorylation of the platelet-derived growth factor beta receptor.FRET-based Visualization of PDGF Receptor Activation at Membrane Microdomains.Targeting receptor tyrosine kinases and their downstream signaling with cell-penetrating peptides in human pulmonary artery smooth muscle and endothelial cells Mitogenic pathways regulated by G protein oncogenes.Adding to the mix: fibroblast growth factor and platelet-derived growth factor receptor pathways as targets in non-small cell lung cancer Developmental expression and distinctive tyrosine phosphorylation of the Eph-related receptor tyrosine kinase Cek9 Ligand-independent activation of the platelet-derived growth factor beta receptor: requirements for bovine papillomavirus E5-induced mitogenic signaling.Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation.Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity Analysis of mutant platelet-derived growth factor receptors expressed in PC12 cells identifies signals governing sodium channel induction during neuronal differentiation.Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively Tyrosine 706 and 807 phosphorylation site mutants in the murine colony-stimulating factor-1 receptor are unaffected in their ability to bind or phosphorylate phosphatidylinositol-3 kinase but show differential defects in their ability to induce earl The beta-PDGF receptor induces neuronal differentiation of PC12 cells.Two conserved cysteine residues are critical for the enzymic function of the human platelet-derived growth factor receptor-beta: evidence for different roles of Cys-822 and Cys-940 in the kinase activity Early phosphoinositide 3-kinase activity is required for late activation of protein kinase Cepsilon in platelet-derived-growth-factor-stimulated cells: evidence for signalling across a large temporal gap.Functional co-operation between the subunits in heterodimeric platelet-derived growth factor receptor complexes.Serine/threonine phosphorylation of the gamma-subunit after activation of the high-affinity Fc receptor for immunoglobulin G.Purification and characterization of a phosphatidylinositol 3-kinase complex from bovine brain by using phosphopeptide affinity columns.The oncogenic FIP1L1-PDGFRα fusion protein displays skewed signaling properties compared to its wild-type PDGFRα counterpart.Platelet-derived growth factor-dependent association of the GTPase-activating protein of Ras and Src.

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P2860

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

http://www.wikidata.org/entity/Q24307555

description

1991 nî lūn-bûn

@nan

1991 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1991 թվականի հունիսին հրատարակված գիտական հոդված

@hy

1991年の論文

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1991年論文

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1991年論文

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1991年論文

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1991年論文

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1991年論文

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1991年论文

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name

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

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Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

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Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

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Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

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type

label

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

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Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

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Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

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Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

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prefLabel

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

@ast

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

@en

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

@en-gb

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

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Molecular Biology of the Cell

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Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

@en

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A Kazlauskas

http://www.w3.org/2001/XMLSchema#string

D L Durden

http://www.w3.org/2001/XMLSchema#string

J A Cooper

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

Binding of GAP to activated PDGF receptors

Two different subunits associate to create isoform-specific platelet-derived growth factor receptors

Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways

Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal human fibroblasts at threonine-654

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

Signal transduction by receptors with tyrosine kinase activity

Signal transduction by the platelet-derived growth factor receptor

Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins

P304

413-25

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scholarly article

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10.1091/MBC.2.6.413

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P433

6

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2

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1991-06-01T00:00:00Z

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21502765

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P698

1653029

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P921

phosphatidylinositol metabolic process

Platelet derived growth factor receptor beta

phosphorylation

P932

361823

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