Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP
about
Indian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levelsHedgehog Signaling in the Maintenance of Cancer Stem CellsStructure of the LdcB LD-Carboxypeptidase Reveals the Molecular Basis of Peptidoglycan RecognitionHedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-active SiteAll Mammalian Hedgehog Proteins Interact with Cell Adhesion Molecule, Down-regulated by Oncogenes (CDO) and Brother of CDO (BOC) in a Conserved MannerStructure of the Fibrillin-1 N-Terminal Domains Suggests that Heparan Sulfate Regulates the Early Stages of Microfibril AssemblyStructural insights into proteoglycan-shaped Hedgehog signalingSynthesis and biological evaluation of novel folic acid receptor-targeted, β-cyclodextrin-based drug complexes for cancer treatmentSmoothened goes molecular: new pieces in the hedgehog signaling puzzleMetabolomic profiling in a Hedgehog Interacting Protein (Hhip) murine model of chronic obstructive pulmonary disease.Recording information on protein complexes in an information management system.Discovery of a eukaryotic pyrroloquinoline quinone-dependent oxidoreductase belonging to a new auxiliary activity family in the database of carbohydrate-active enzymesIdentification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP.Molecular dynamics simulations of sonic hedgehog-receptor and inhibitor complexes and their applications for potential anticancer agent discoveryDesign and characterization of a photo-activatable hedgehog probe that mimics the natural lipidated form.A gene signature based method for identifying subtypes and subtype-specific drivers in cancer with an application to medulloblastoma.Signaling domain of Sonic Hedgehog as cannibalistic calcium-regulated zinc-peptidaseSecreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function46,XY Gonadal Dysgenesis due to a Homozygous Mutation in Desert Hedgehog (DHH) Identified by Exome SequencingHedgehog secretion and signal transduction in vertebrates.MicroRNA Expression Profiling in CCl₄-Induced Liver Fibrosis of Mus musculus.Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling.Non-cell-autonomous signaling by Shh in tumors: challenges and opportunities for therapeutic targets.Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer.Interactions between Hedgehog proteins and their binding partners come into view.Hedgehog signaling in the liver.Expression of recombinant glycoproteins in mammalian cells: towards an integrative approach to structural biology.Pseudoproteases: mechanisms and function.Chronic Obstructive Pulmonary Disease Genetics: A Review of the Past and a Look Into the FutureAn emerging role of Sonic hedgehog shedding as a modulator of heparan sulfate interactionsIron excess limits HHIPL-2 gene expression and decreases osteoblastic activity in human MG-63 cells.The influence of metal-ion binding on the structure and surface composition of Sonic Hedgehog: a combined classical and hybrid QM/MM MD study.Discovery and evaluation of potential sonic hedgehog signaling pathway inhibitors using pharmacophore modeling and molecular dynamics simulations.Biophysical characterisation of the novel zinc binding property in Suppressor of Fused.Cysteine-rich domains related to Frizzled receptors and Hedgehog-interacting proteins.Hedgehog-Interacting Protein (HIP) Regulates Apoptosis Evasion and Angiogenic Function of Late Endothelial Progenitor Cells.Automation of large scale transient protein expression in mammalian cells.Shh-mediated degradation of Hhip allows cell autonomous and non-cell autonomous Shh signalling.Survey of the 2009 commercial optical biosensor literature.The Binding Mode of the Sonic Hedgehog Inhibitor Robotnikinin, a Combined Docking and QM/MM MD Study.
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P2860
Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural insights into hedge ...... gehog-interacting protein HHIP
@ast
Structural insights into hedge ...... gehog-interacting protein HHIP
@en
Structural insights into hedge ...... gehog-interacting protein HHIP
@en-gb
Structural insights into hedge ...... gehog-interacting protein HHIP
@nl
type
label
Structural insights into hedge ...... gehog-interacting protein HHIP
@ast
Structural insights into hedge ...... gehog-interacting protein HHIP
@en
Structural insights into hedge ...... gehog-interacting protein HHIP
@en-gb
Structural insights into hedge ...... gehog-interacting protein HHIP
@nl
prefLabel
Structural insights into hedge ...... gehog-interacting protein HHIP
@ast
Structural insights into hedge ...... gehog-interacting protein HHIP
@en
Structural insights into hedge ...... gehog-interacting protein HHIP
@en-gb
Structural insights into hedge ...... gehog-interacting protein HHIP
@nl
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P2860
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Structural insights into hedge ...... gehog-interacting protein HHIP
@en
P2093
A Radu Aricescu
Benjamin Bishop
Chris A O'Callaghan
E Yvonne Jones
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P2888
P304
P3181
P356
10.1038/NSMB.1607
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P577
2009-07-01T00:00:00Z
P5875
P6179
1016952186