Non-cell-autonomous signaling by Shh in tumors: challenges and opportunities for therapeutic targets.
about
Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development.Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition.Temozolomide resistance in glioblastoma occurs by miRNA-9-targeted PTCH1, independent of sonic hedgehog level.
P2860
Non-cell-autonomous signaling by Shh in tumors: challenges and opportunities for therapeutic targets.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Non-cell-autonomous signaling ...... ities for therapeutic targets.
@en
Non-cell-autonomous signaling ...... ities for therapeutic targets.
@nl
type
label
Non-cell-autonomous signaling ...... ities for therapeutic targets.
@en
Non-cell-autonomous signaling ...... ities for therapeutic targets.
@nl
prefLabel
Non-cell-autonomous signaling ...... ities for therapeutic targets.
@en
Non-cell-autonomous signaling ...... ities for therapeutic targets.
@nl
P2860
P1476
Non-cell-autonomous signaling ...... nities for therapeutic targets
@en
P2093
Maarten F Bijlsma
P2860
P304
P356
10.1517/14728222.2010.497488
P407
P50
P577
2010-07-01T00:00:00Z