Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1
about
Activation of 2' 5'-oligoadenylate synthetase by stem loops at the 5'-end of the West Nile virus genomeCyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP SynthaseStructure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate ImmunityStructural mechanism of cytosolic DNA sensing by cGASCyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced OligomerizationStructure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN ResponseDynamic light scattering: a practical guide and applications in biomedical sciences.Viral phosphodiesterases that antagonize double-stranded RNA signaling to RNase L by degrading 2-5AMolecular evolutionary and structural analysis of the cytosolic DNA sensor cGAS and STINGStructure-guided reprogramming of human cGAS dinucleotide linkage specificity.The mechanism of double-stranded DNA sensing through the cGAS-STING pathwayA novel RNA molecular signature for activation of 2'-5' oligoadenylate synthetase-1Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3Structural biology of innate immunity.OASes and STING: adaptive evolution in concertOverlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape.Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signalingActivation of RNase L is dependent on OAS3 expression during infection with diverse human virusesContrasted patterns of variation and evolutionary convergence at the antiviral OAS1 gene in old world primates.Ribosome•RelA structures reveal the mechanism of stringent response activation.Intracellular detection of viral nucleic acids.Cyclic dinucleotides and the innate immune response.Cyclic di-nucleotide signaling enters the eukaryote domain.OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids.The 2'-5'-oligoadenylate synthetase 3 enzyme potently synthesizes the 2'-5'-oligoadenylates required for RNase L activation.Gut response induced by weaning in piglet features marked changes in immune and inflammatory response.Rapid RNase L-Driven Arrest of Protein Synthesis in the dsRNA Response without Degradation of Translation Machinery.High Anti-Dengue Virus Activity of the OAS Gene Family Is Associated With Increased Severity of Dengue.Functional evolution of the OAS1 viral sensor: Insights from old world primates.Keeping your armour intact: how HIV-1 evades detection by the innate immune system: HIV-1 capsid controls detection of reverse transcription products by the cytosolic DNA sensor cGAS.Building unique bonds to fight misplaced DNACrystal structure of the novel di-nucleotide cyclase from Vibrio cholerae (DncV) responsible for synthesizing a hybrid cyclic GMP-AMP.The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.Heterozygous Mutations in OAS1 Cause Infantile-Onset Pulmonary Alveolar Proteinosis with Hypogammaglobulinemia.Immunology: Cytosolic DNA sensing unraveled.Evolutionary Analysis Provides Insight Into the Origin and Adaptation of HCV.Proteomic Identification of Heat Shock-Induced Danger Signals in a Melanoma Cell Lysate Used in Dendritic Cell-Based Cancer Immunotherapy.Molecular Mechanisms for the Adaptive Switching Between the OAS/RNase L and OASL/RIG-I Pathways in Birds and Mammals.OAS1 binds viral dsRNAOAS1 produces oligoadenylates
P2860
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P2860
Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@ast
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@en
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@en-gb
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@nl
type
label
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@ast
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@en
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@en-gb
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@nl
prefLabel
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@ast
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@en
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@en-gb
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@nl
P2093
P2860
P3181
P356
P1476
Structural basis for cytosolic ...... an oligoadenylate synthetase 1
@en
P2093
Alexei Korennykh
Jesse Donovan
Matthew Dufner
P2860
P304
P3181
P356
10.1073/PNAS.1218528110
P407
P577
2013-01-29T00:00:00Z