Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response - sprookjes - yvandenbroek - TriplyDB

Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

http://www.wikidata.org/entity/Q27681927

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The Roles of RNase-L in Antimicrobial Immunity and the Cytoskeleton-Associated Innate Response Crystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain that antagonizes RNase L activation In Vivo Cleavage Map Illuminates the Central Role of RNase E in Coding and Non-coding RNA Pathways Pseudokinases: update on their functions and evaluation as new drug targets.Molecular mechanisms of human IRE1 activation through dimerization and ligand binding RNase L targets distinct sites in influenza A virus RNAs.Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death.Genome-wide mRNA processing in methanogenic archaea reveals post-transcriptional regulation of ribosomal protein synthesis.RNase L interacts with Filamin A to regulate actin dynamics and barrier function for viral entry RNase L attenuates mitogen-stimulated gene expression via transcriptional and post-transcriptional mechanisms to limit the proliferative response Functionally conserved architecture of hepatitis C virus RNA genomes.Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3 Structural biology of innate immunity.OASes and STING: adaptive evolution in concert Human RNase L tunes gene expression by selectively destabilizing the microRNA-regulated transcriptome.Structural Basis for the Non-catalytic Functions of Protein Kinases.The CRISPR-associated Csx1 protein of Pyrococcus furiosus is an adenosine-specific endoribonuclease.Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6 RNase L Suppresses Androgen Receptor Signaling, Cell Migration and Matrix Metalloproteinase Activity in Prostate Cancer Cells.Can't RIDD off viruses.OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids.METABOLISM. S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction.Emerging roles for RNA degradation in viral replication and antiviral defense.Rapid RNase L-Driven Arrest of Protein Synthesis in the dsRNA Response without Degradation of Translation Machinery.Nucleotide-binding mechanisms in pseudokinases.Evolutionary adaptation revealed by comparative genome analysis of woolly mammoths and elephants.Sequence-Specific Sensing of Nucleic Acids.The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation.Curcumin, a natural antioxidant, acts as a noncompetitive inhibitor of human RNase L in presence of its cofactor 2-5A in vitro.Grc3 programs the essential endoribonuclease Las1 for specific RNA cleavage.Nuclease integrated kinase super assemblies (NiKs) and their role in RNA processing.A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L.Molecular Mechanisms for the Adaptive Switching Between the OAS/RNase L and OASL/RIG-I Pathways in Birds and Mammals.RNASEL binds 2'-5' oligoadenylate

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Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

http://www.wikidata.org/entity/Q27681927

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2014 nî lūn-bûn

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2014 թուականի Մարտին հրատարակուած գիտական յօդուած

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2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

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Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

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Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

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type

label

Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

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Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

@en

Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

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prefLabel

Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

@ast

Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

@en

Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response

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SCIENCE.1249845

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Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response

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Alexei Korennykh

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Alisha Chitrakar

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Gena Whitney

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Jesse Donovan

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Yuchen Han

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P2860

Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1

Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection

The protein kinase complement of the human genome

Alternative function of a protein kinase homology domain in 2', 5'-oligoadenylate dependent RNase L

New insights into the role of RNase L in innate immunity

Hepatitis C virus RNA: Dinucleotide frequencies and cleavage by RNase L

Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing

The unfolded protein response signals through high-order assembly of Ire1

Structural and functional basis for RNA cleavage by Ire1

Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity

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