Menin associates with FANCD2, a protein involved in repair of DNA damage
about
Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cellsLeukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expressionDirect binding of DNA by tumor suppressor meninMenin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitorsThe tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression.Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalizationInherited pancreatic endocrine tumor syndromes: advances in molecular pathogenesis, diagnosis, management, and controversiesCrystal structure of menin reveals binding site for mixed lineage leukemia (MLL) proteinThe same pocket in menin binds both MLL and JUND but has opposite effects on transcriptionMEN1, MEN4, and Carney Complex: Pathology and Molecular GeneticsMenin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4cTumor suppressor menin regulates expression of insulin-like growth factor binding protein 2Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cellsMenin induces apoptosis in murine embryonic fibroblastsConditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissuesIdentification of somatic mutations in parathyroid tumors using whole-exome sequencingSuppression of lung adenocarcinoma through menin and polycomb gene-mediated repression of growth factor pleiotrophin.c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis.MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.Menin links the stress response to genome stability in Drosophila melanogasterMultiple endocrine neoplasia type 1 associated with breast cancer: A case report and review of the literatureThe menin tumor suppressor protein is phosphorylated in response to DNA damageRegulation of cyclin B2 expression and cell cycle G2/m transition by meninMenin is a regulator of the stress response in Drosophila melanogasterMenin and p53 have non-synergistic effects on tumorigenesis in miceChallenges and opportunities in targeting the menin-MLL interaction.Menin represses tumorigenesis via repressing cell proliferation.An activation force-based affinity measure for analyzing complex networks.Variable clinical expression in patients with a germline MEN1 disease gene mutation: clues to a genotype-phenotype correlation.Interplay between menin and K-Ras in regulating lung adenocarcinoma.MEN1 and FANCD2 mediate distinct mechanisms of DNA crosslink repair.Ovarian cancer: in search of better marker systems based on DNA repair defectsIn search of tumor suppressing functions of meninGenetics of pancreatic neuroendocrine tumors: implications for the clinic.Multiple endocrine neoplasia type 1 (MEN1) as a cancer predisposition syndrome: clues into the mechanisms of MEN1-related carcinogenesis.MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair.Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells.Menin is required for optimal processing of the microRNA let-7a.The Fanconi anemia ID2 complex: dueling saxes at the crossroads.miR-24 Inhibition Increases Menin Expression and Decreases Cholangiocarcinoma Proliferation.
P2860
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P248
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P2860
Menin associates with FANCD2, a protein involved in repair of DNA damage
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
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2003年論文
@zh-mo
2003年論文
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2003年论文
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name
Menin associates with FANCD2, a protein involved in repair of DNA damage
@ast
Menin associates with FANCD2, a protein involved in repair of DNA damage
@en
Menin associates with FANCD2, a protein involved in repair of DNA damage
@en-gb
Menin associates with FANCD2, a protein involved in repair of DNA damage
@nl
type
label
Menin associates with FANCD2, a protein involved in repair of DNA damage
@ast
Menin associates with FANCD2, a protein involved in repair of DNA damage
@en
Menin associates with FANCD2, a protein involved in repair of DNA damage
@en-gb
Menin associates with FANCD2, a protein involved in repair of DNA damage
@nl
prefLabel
Menin associates with FANCD2, a protein involved in repair of DNA damage
@ast
Menin associates with FANCD2, a protein involved in repair of DNA damage
@en
Menin associates with FANCD2, a protein involved in repair of DNA damage
@en-gb
Menin associates with FANCD2, a protein involved in repair of DNA damage
@nl
P2093
P921
P1433
P1476
Menin associates with FANCD2, a protein involved in repair of DNA damage
@en
P2093
Alan D D'Andrea
Albert C Silva
Robert W Schnepp
Shenghao Jin
Stephen M Sykes
Xianxin Hua
P304
P407
P577
2003-07-01T00:00:00Z