Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testes
about
Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of beta2-chimaerin, a 'non-protein kinase C' phorbol ester receptorHuman CHN1 mutations hyperactivate alpha2-chimaerin and cause Duane's retraction syndromebeta2-chimaerin is a novel target for diacylglycerol: binding properties and changes in subcellular localization mediated by ligand binding to its C1 domainChimaerins, novel non-protein kinase C phorbol ester receptors, associate with Tmp21-I (p23): evidence for a novel anchoring mechanism involving the chimaerin C1 domainPhorbol esters and related analogs regulate the subcellular localization of beta 2-chimaerin, a non-protein kinase C phorbol ester receptorBeta2-chimaerin is a high affinity receptor for the phorbol ester tumor promotersMolecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) familyA dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activitiesIdentification and characterization of a novel Rab GTPase-activating protein in spermatidsVav: function and regulation in hematopoietic cell signaling.Polarity proteins and cell-cell interactions in the testis.A new autosomal recessive retinitis pigmentosa locus maps on chromosome 2q31-q33.Human genetic disorders of axon guidance.Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters.Identification of α-chimaerin as a candidate gene for critical period neuronal plasticity in cat and mouse visual cortex.Screening of nine candidate genes for autism on chromosome 2q reveals rare nonsynonymous variants in the cAMP-GEFII gene.MgcRacGAP, a new human GTPase-activating protein for Rac and Cdc42 similar to Drosophila rotundRacGAP gene product, is expressed in male germ cells.Chimaerin suppresses Rac1 activation at the apical membrane to maintain the cyst structureAlpha1-chimaerin, a Rac1 GTPase-activating protein, is expressed at reduced mRNA levels in the brain of Alzheimer's disease patients.Chimaerin and Rac regulate cell number, adherens junctions, and ERK MAP kinase signaling in the Drosophila eye.Alpha2-chimaerin interacts with EphA4 and regulates EphA4-dependent growth cone collapse.Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: possible role of protein phosphorylationRole of chimaerins, a group of Rac-specific GTPase activating proteins, in T-cell receptor signaling.Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglyceridesCurrent knowledge of the large RhoGAP family of proteins.The role of small GTPases in neuronal morphogenesis and polarity.Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets.Characterization of the cysteine-rich region of the Caenorhabditis elegans protein Unc-13 as a high affinity phorbol ester receptor. Analysis of ligand-binding interactions, lipid cofactor requirements, and inhibitor sensitivity.Promoter region of the transcriptional unit for human alpha 1-chimaerin, a neuron-specific GTPase-activating protein for p21rac.RhoGTPases at the synapse: An embarrassment of choice.Regulation of actin cytoskeleton in lymphocytes: PKC-delta disrupts IL-3-induced membrane ruffles downstream of Rac1.Selective up-regulation of alpha 1-chimaerin mRNA in SK-N-SH neuroblastoma cells by K+/-induced depolarisation.Attenuation of p53 expression and Bax down-regulation during phorbol ester mediated inhibition of apoptosisRegional localization and developmental expression of the BCR gene in rodent brain.The RacGAP β-Chimaerin is essential for cerebellar granule cell migration.The human neuronal alpha 1-chimaerin gene contains a position-dependent negative regulatory element in the first exon.Impact of energy restriction during late gestation on the muscle and blood transcriptome of beef calves after preconditioning
P2860
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P2860
Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testes
description
1993 nî lūn-bûn
@nan
1993 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@ast
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@en
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@en-gb
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@nl
type
label
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@ast
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@en
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@en-gb
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@nl
prefLabel
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@ast
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@en
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@en-gb
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@nl
P2093
P2860
P356
P1476
Alpha 2-chimerin, an SH2-conta ...... ed in brain regions and testes
@en
P2093
G J Michael
P2860
P304
P356
10.1128/MCB.13.8.4986
P407
P50
P577
1993-08-01T00:00:00Z