Characterization of the cysteine-rich region of the Caenorhabditis elegans protein Unc-13 as a high affinity phorbol ester receptor. Analysis of ligand-binding interactions, lipid cofactor requirements, and inhibitor sensitivity.
about
Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34Role of the regulatory domain of protein kinase D2 in phorbol ester binding, catalytic activity, and nucleocytoplasmic shuttlingThe extended protein kinase C superfamilyRole of the Doc2 alpha-Munc13-1 interaction in the neurotransmitter release processCardiac cAMP: production, hydrolysis, modulation and detectionPhorbol esters and related analogs regulate the subcellular localization of beta 2-chimaerin, a non-protein kinase C phorbol ester receptorBeta2-chimaerin is a high affinity receptor for the phorbol ester tumor promotersMammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteinsDirect interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxinAmphitropic proteins: regulation by reversible membrane interactions (review).Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters.Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis.Molecular mechanisms of neurotransmitter release.Physical and functional interactions of Doc2 and Munc13 in Ca2+-dependent exocytotic machinery.Characterization of the interaction of phorbol esters with the C1 domain of MRCK (myotonic dystrophy kinase-related Cdc42 binding kinase) alpha/beta.Expression of multiple UNC-13 proteins in the Caenorhabditis elegans nervous system.Phorbol esters and neurotransmitter release: more than just protein kinase C?Proteomics analysis of the expression of neurogranin in murine neuroblastoma (Neuro-2a) cells reveals its involvement for cell differentiation.Differential effects of bryostatin 1 and 12-O-tetradecanoylphorbol-13-acetate on the regulation and activation of RasGRP1 in mouse epidermal keratinocytes.Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cellsLocalized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis.Residues in the second cysteine-rich region of protein kinase C delta relevant to phorbol ester binding as revealed by site-directed mutagenesis.C1 domain-targeted isophthalates as protein kinase C modulators: structure-based design, structure-activity relationships and biological activities.Protein kinase C in cancer: The top five unanswered questions.Differential membrane binding and diacylglycerol recognition by C1 domains of RasGRPs.Parathyroid hormone receptor internalization is independent of protein kinase A and phospholipase C activation.NO-released zinc supports the simultaneous binding of Raf-1 and PKCγ cysteine-rich domains to HINT1 protein at the mu-opioid receptor.Protein kinase D activation by deletion of its cysteine-rich motifs.Role of PKC in the regulation of gonadotropin subunit mRNA levels: interaction with two native forms of gonadotropin-releasing hormone.O-Silylated C3-halohydrins as a novel class of protected building blocks for total, regio- and stereocontrolled synthesis of glycerolipid frameworks.UNC-13 is required for synaptic vesicle fusion in C. elegans.PKC-permitted elevation of sarcolemmal KATP concentration may explain female-specific resistance to myocardial infarction.Critical Role of Trp-588 of Presynaptic Munc13-1 for Ligand Binding and Membrane Translocation.Resveratrol inhibits phorbol ester-induced membrane translocation of presynaptic Munc13-1.
P2860
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P2860
Characterization of the cysteine-rich region of the Caenorhabditis elegans protein Unc-13 as a high affinity phorbol ester receptor. Analysis of ligand-binding interactions, lipid cofactor requirements, and inhibitor sensitivity.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Characterization of the cystei ...... ts, and inhibitor sensitivity.
@en
type
label
Characterization of the cystei ...... ts, and inhibitor sensitivity.
@en
prefLabel
Characterization of the cystei ...... ts, and inhibitor sensitivity.
@en
P2093
P2860
P356
P1476
Characterization of the cystei ...... ts, and inhibitor sensitivity.
@en
P2093
M G Kazanietz
P M Blumberg
P2860
P304
10777-10783
P356
10.1074/JBC.270.18.10777
P407
P577
1995-05-01T00:00:00Z