Control of telomere length by the human telomeric protein TRF1
about
P1343
The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymeraseTIN2, a new regulator of telomere length in human cellsTelomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumorsTelomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaksTANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpressionRole for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeresThe telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complexInvolvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindleThe F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenanceNek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblastsVault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivoTargeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2PTOP interacts with POT1 and regulates its localization to telomeresHigher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2Rap1 affects the length and heterogeneity of human telomeresPOT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complexA critical role for TPP1 and TIN2 interaction in high-order telomeric complex assemblyProtein requirements for sister telomere association in human cellsStructural basis of selective ubiquitination of TRF1 by SCFFbx4Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulationCharacterization of interactions between PinX1 and human telomerase subunits hTERT and hTRTelosome, a mammalian telomere-associated complex formed by multiple telomeric proteinsThe human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activityPOT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substratesTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationCharacterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosisIn vivo stoichiometry of shelterin componentsTelomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeatsHuman telomeres contain two distinct Myb-related proteins, TRF1 and TRF2PinX1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse Transcriptase (hTERT) plays dual rolesPOT1 association with TRF2 regulates telomere lengthCharacterization of the DNA binding specificity of Shelterin complexesHow the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structuresTelomere dysfunction and cell survival: roles for distinct TIN2-containing complexesHuman protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitroThe human Rap1 protein complex and modulation of telomere lengthPOT1 and TRF2 cooperate to maintain telomeric integrityMyb-related Schizosaccharomyces pombe cdc5p is structurally and functionally conserved in eukaryotes.Human telomerase and its regulation
P2860
Q22010521-E0C00347-DC8F-4345-966B-1C4740C770E9Q22010863-16FA519A-5986-46F9-9B33-866ADD2E712DQ24291157-1DA1B6E7-436A-4CF1-B2F5-0A356746624AQ24291265-9BD79011-3853-4BAF-97E9-870E1E7B9BC7Q24291448-CDF18FA5-2184-4C5F-88B7-5B9FB7304E62Q24291989-003DE214-82EA-4F26-9E47-B1410F200CB4Q24292328-4B943561-F821-49EE-B4A6-DBA309D1C2D3Q24292755-C34B6F66-25EF-4095-85B4-29D8B53DA9DEQ24293666-EC5A8AC3-9F41-4346-980B-D0E0D5E948C0Q24293991-0F6594A4-2F2F-431A-9043-2DD25A6FC079Q24294537-253369C8-9189-47C8-9ABA-B558F3F63C77Q24294689-C5F7BADC-A791-48E7-9710-54CB40E8195BQ24295044-EF5A477C-F251-437F-8379-40B3868A8251Q24295162-4C149838-9FDE-474E-97BC-FAB243085D27Q24297181-130CA52C-41FB-4841-B1BA-B2C36FC8FCA6Q24298023-51C3C870-FB10-457B-9DB6-044A88598FFDQ24298357-7C06EC51-E3FA-4967-ACAC-8FAAF703B3F1Q24298475-607413D0-A91B-4B8D-8FA8-5F8C67086FF4Q24298717-B6EA350A-DE72-4B1D-AD17-0EF946B9B042Q24299395-0CFD1584-43FD-47AE-8FBE-0430A129AAA1Q24303593-CEC0D554-12FD-4132-885C-2D7A8218E59BQ24304902-8C0E1D15-1980-4303-A3E2-2381A57E2281Q24304989-78AF56E9-5623-45D6-A9EA-04F933242567Q24306780-53FB0471-3C74-4BA0-8FA8-718056885D45Q24308828-67229F4E-A7E3-4ADA-BF00-B939D57C3F8DQ24310189-1D1663B3-1B86-4E57-9AA7-73ADBE18B6ACQ24311518-1D35F483-D762-42CA-B556-8271EA296B0FQ24312021-5B317D33-AD75-4144-BC9E-13D45BC2C64AQ24315056-AFAE5B96-EC17-458C-B8A3-3E9F02F2CB85Q24317670-4950028E-D439-49CA-9491-093596A8438CQ24319715-5B0C72A4-D452-452B-B07B-669C19B6FE9BQ24320254-DEDDF140-15FC-4AF1-8822-E6486291E092Q24323345-7D050FCB-B1E6-41D8-8BE0-8FBFC0476C4BQ24323494-32C0467C-BA9F-4C4A-B06D-0349C47682C4Q24336203-762A30AF-ECB3-4C7D-9B72-CD9CDB87B9D3Q24337394-5463FC2B-6E62-4BE2-B443-A37D1159C4BBQ24337452-2FB2DF7A-C793-4B7F-95F6-C4F58468B712Q24338505-EFEF0B7E-6054-4D6C-9BE1-B16C6D344F6CQ24522549-FECA1F92-38D3-4615-987D-CA223EFCBC54Q24533247-0946B069-2DC3-4236-AC30-8881194F8BEF
P2860
Control of telomere length by the human telomeric protein TRF1
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Control of telomere length by the human telomeric protein TRF1
@ast
Control of telomere length by the human telomeric protein TRF1
@en
Control of telomere length by the human telomeric protein TRF1
@en-gb
Control of telomere length by the human telomeric protein TRF1
@nl
type
label
Control of telomere length by the human telomeric protein TRF1
@ast
Control of telomere length by the human telomeric protein TRF1
@en
Control of telomere length by the human telomeric protein TRF1
@en-gb
Control of telomere length by the human telomeric protein TRF1
@nl
prefLabel
Control of telomere length by the human telomeric protein TRF1
@ast
Control of telomere length by the human telomeric protein TRF1
@en
Control of telomere length by the human telomeric protein TRF1
@en-gb
Control of telomere length by the human telomeric protein TRF1
@nl
P3181
P356
P1433
P1476
Control of telomere length by the human telomeric protein TRF1
@en
P2093
B van Steensel
P2888
P3181
P356
10.1038/385740A0
P407
P577
1997-02-20T00:00:00Z
P5875
P6179
1050529956