E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
about
Nuclear export regulation of COP1 by 14-3-3σ in response to DNA damageCOP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σSUMOylation and SUMO-interacting motif (SIM) of metastasis tumor antigen 1 (MTA1) synergistically regulate its transcriptional repressor functionATP-dependent chromatin remodeling complexes as novel targets for cancer therapyThe NuRD architecturePhysiological functions of MTA family of proteinsStructure, expression and functions of MTA genesMORC2 signaling integrates phosphorylation-dependent, ATPase-coupled chromatin remodeling during the DNA damage responseRevelation of p53-independent function of MTA1 in DNA damage response via modulation of the p21 WAF1-proliferating cell nuclear antigen pathway.Gene profiling of MTA1 identifies novel gene targets and functions.Requirement of MTA1 in ATR-mediated DNA damage checkpoint function.Mi-2/NuRD complex making inroads into DNA-damage response pathwayCancer biology and NuRD: a multifaceted chromatin remodelling complexBidirectional autoregulatory mechanism of metastasis-associated protein 1-alternative reading frame pathway in oncogenesis.Metastasis-associated protein 1/nucleosome remodeling and histone deacetylase complex in cancerRepression of NR4A1 by a chromatin modifier promotes docetaxel resistance in PC-3 human prostate cancer cells.Role of MTA1 in cancer progression and metastasisSubcellular localization of MTA proteins in normal and cancer cells.SLUG-induced elevation of D1 cyclin in breast cancer cells through the inhibition of its ubiquitination.MTA1--a stress response protein: a master regulator of gene expression and cancer cell behavior.Identification of novel gene targets and functions of p21-activated kinase 1 during DNA damage by gene expression profilingMTA1 coregulator regulates p53 stability and function.Metastasis-associated protein 1 drives tumor cell migration and invasion through transcriptional repression of RING finger protein 144A14-3-3sigma exerts tumor-suppressor activity mediated by regulation of COP1 stability.MTA1 regulation of ERβ pathway in salivary gland carcinoma cells.COP1 enhances ubiquitin-mediated degradation of p27Kip1 to promote cancer cell growth.Structural Basis for the Non-catalytic Functions of Protein Kinases.Connecting chromatin modifying factors to DNA damage response.Interaction of constitutive photomorphogenesis 1 protein with protein-tyrosine phosphatase 1B suppresses protein-tyrosine phosphatase 1B activity and enhances insulin signaling.Mutant p53 protects ETS2 from non-canonical COP1/DET1 dependent degradation.E3 ubiquitin ligase RFWD2 controls lung branching through protein-level regulation of ETV transcription factors.CHD chromatin remodelers and the transcription cycle.Spotlight on the role of COP1 in tumorigenesis.Epigenetics in radiation-induced fibrosis.Metastatic tumor antigen in hepatocellular carcinoma: golden roads toward personalized medicine.MTA family of proteins in DNA damage response: mechanistic insights and potential applications.Molecular functions and significance of the MTA family in hormone-independent cancer.HuCOP1 contributes to the regulation of DNA repair in keratinocytes.Constitutive photomorphogenesis protein 1 (COP1) and COP9 signalosome, evolutionarily conserved photomorphogenic proteins as possible targets of melatonin.Poly(ADP-ribosyl)ation of p53 induces gene-specific transcriptional repression of MTA1.
P2860
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P248
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P2860
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@ast
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@en
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@en-gb
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@nl
type
label
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@ast
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@en
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@en-gb
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@nl
prefLabel
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@ast
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@en
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@en-gb
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@nl
P2093
P2860
P921
P356
P1476
E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1
@en
P2093
Da-Qiang Li
Kazufumi Ohshiro
Mong-Hong Lee
Rakesh Kumar
Sirigiri Divijendra Natha Reddy
Suresh B Pakala
Suresh K Rayala
Yanping Zhang
P2860
P304
P356
10.1073/PNAS.0908027106
P407
P577
2009-10-13T00:00:00Z