about
IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesisCooperative epigenetic modulation by cancer amplicon genesJakinibs: a new class of kinase inhibitors in cancer and autoimmune diseaseGenome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility lociEfficacy and safety of the oral Janus kinase inhibitor peficitinib (ASP015K) monotherapy in patients with moderate to severe rheumatoid arthritis in Japan: a 12-week, randomised, double-blind, placebo-controlled phase IIb studySignaling Pathways in Thyroid Cancer and Their Therapeutic ImplicationsProfile of tofacitinib citrate and its potential in the treatment of moderate-to-severe chronic plaque psoriasisCurrent concepts in the management of rheumatoid arthritisStaphylococcal Superantigens Spark Host-Mediated Danger SignalsPI3K/Akt/mTOR, a pathway less recognized for staphylococcal superantigen-induced toxicitySTAT3 and the Hyper-IgE syndrome: Clinical presentation, genetic origin, pathogenesis, novel findings and remaining uncertaintiesMechanisms of chronic JAK-STAT3-SOCS3 signaling in obesityDry eye: an inflammatory ocular diseaseProtein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligasesGenetic update on inflammatory factors in ulcerative colitis: Review of the current literatureBacterial and fungal pattern recognition receptors in homologous innate signaling pathways of insects and mammalsJakpot! New small molecules in autoimmune and inflammatory diseasesInflammatory pathways of importance for management of inflammatory bowel diseaseEpistasis and immunity: the role of genetic interactions in autoimmune diseasesHyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitisGenetics of SCIDCrystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617FStructure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinasesNovel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndromeDangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancerBiochemical and computational analysis of LNX1 interacting proteinsThe tyrphostin agent AG490 prevents and reverses type 1 diabetes in NOD miceGlucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activationTyrosine kinase inhibitors for the treatment of rheumatoid arthritisEfficacious intermittent dosing of a novel JAK2 inhibitor in mouse models of polycythemia veraEssential biphasic role for JAK3 catalytic activity in IL-2 receptor signalingNeutrophil cell surface receptors and their intracellular signal transduction pathways.Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies Jak inhibitors effective in mitigating multifaceted toxic responses.Biology and clinical management of myeloproliferative neoplasms and development of the JAK inhibitor ruxolitinibSelective Janus associated kinase 1 inhibition as a therapeutic target in myelofibrosis.Evaluation of a DLA-79 allele associated with multiple immune-mediated diseases in dogs.NSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes.Efficacy and safety of tofacitinib in patients with active rheumatoid arthritis: review of key Phase 2 studies
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Janus kinases in immune cell signaling
@ast
Janus kinases in immune cell signaling
@en
Janus kinases in immune cell signaling
@en-gb
Janus kinases in immune cell signaling
@nl
type
label
Janus kinases in immune cell signaling
@ast
Janus kinases in immune cell signaling
@en
Janus kinases in immune cell signaling
@en-gb
Janus kinases in immune cell signaling
@nl
prefLabel
Janus kinases in immune cell signaling
@ast
Janus kinases in immune cell signaling
@en
Janus kinases in immune cell signaling
@en-gb
Janus kinases in immune cell signaling
@nl
P2093
P2860
P3181
P1476
Janus kinases in immune cell signaling
@en
P2093
Arian Laurence
John J O'Shea
Kamran Ghoreschi
P2860
P304
P3181
P356
10.1111/J.1600-065X.2008.00754.X
P407
P577
2009-03-01T00:00:00Z