Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
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Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2Exome sequencing identifies DLG1 as a novel gene for potential susceptibility to Crohn's disease in a Chinese family studyGenetic Association of Peptidoglycan Recognition Protein Variants with Inflammatory Bowel DiseaseComparison of family history and SNPs for predicting risk of complex diseaseHuman genetics and genomics a decade after the release of the draft sequence of the human genomeA modular organization of the human intestinal mucosal microbiota and its association with inflammatory bowel diseaseThe shock of the new: progress in schizophrenia genomicsCrohn's disease risk alleles on the NOD2 locus have been maintained by natural selection on standing variationRecent Insights Into the Genetics of Inflammatory Bowel DiseaseHost-microbe interactions have shaped the genetic architecture of inflammatory bowel diseaseA subset-based approach improves power and interpretation for the combined analysis of genetic association studies of heterogeneous traitsGWAS of 126,559 individuals identifies genetic variants associated with educational attainmentTNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosisProtein characterization of a candidate mechanism SNP for Crohn's disease: the macrophage stimulating protein R689C substitutionMutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodiesThe intermediate filament protein, vimentin, is a regulator of NOD2 activityThe kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel diseaseThe NHGRI GWAS Catalog, a curated resource of SNP-trait associationsDeep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel diseaseFive years of GWAS discoveryImmunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variantsThe emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findingsDense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosisStructural and molecular features of intestinal strictures in rats with Crohn's-like diseaseNovel biomarkers of fibrosis in Crohn's diseaseManipulation of DNA Repair Proficiency in Mouse Models of Colorectal CancerMucosal Interactions between Genetics, Diet, and Microbiome in Inflammatory Bowel DiseaseThe role for protein tyrosine phosphatase non-receptor type 22 in regulating intestinal homeostasisThe Role of the C-Clamp in Wnt-Related Colorectal CancersThe Impact of Evolutionary Driving Forces on Human Complex Diseases: A Population Genetics ApproachStem cell-based therapies in inflammatory bowel disease: promises and pitfallsGenetic Influences on the Development of Fibrosis in Crohn's DiseaseMicroRNAs: Novel immunotherapeutic targets in colorectal carcinomaChronic inflammatory systemic diseases: An evolutionary trade-off between acutely beneficial but chronically harmful programsApplication of computational methods in genetic study of inflammatory bowel diseaseMechanisms of Microbe-Host Interaction in Crohn's Disease: Dysbiosis vs. Pathobiont SelectionType I/II cytokines, JAKs, and new strategies for treating autoimmune diseasesIntestinal Behçet's Disease: A True Inflammatory Bowel Disease or Merely an Intestinal Complication of Systemic Vasculitis?Immunogenicity and mechanisms impairing the response to vaccines in inflammatory bowel diseaseTribbles-1: a novel regulator of hepatic lipid metabolism in humans
P2860
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P248
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P2860
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Genome-wide meta-analysis incr ...... 's disease susceptibility loci
@ast
Genome-wide meta-analysis incr ...... 's disease susceptibility loci
@en
Genome-wide meta-analysis incr ...... 's disease susceptibility loci
@nl
type
label
Genome-wide meta-analysis incr ...... 's disease susceptibility loci
@ast
Genome-wide meta-analysis incr ...... 's disease susceptibility loci
@en
Genome-wide meta-analysis incr ...... 's disease susceptibility loci
@nl
prefLabel
Genome-wide meta-analysis incr ...... 's disease susceptibility loci
@ast
Genome-wide meta-analysis incr ...... 's disease susceptibility loci
@en
Genome-wide meta-analysis incr ...... 's disease susceptibility loci
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Genome-wide meta-analysis incr ...... 's disease susceptibility loci
@en
P2093
A Hillary Steinhart
Albert Cohen
Amir Karban
Andre Franke
Andre Van Gossum
Anne M Griffiths
Anne Phillips
Arie Levine
Carsten Büning
Cathryn Edwards
P2860
P2888
P304
P3181
P356
10.1038/NG.717
P407
P50
P577
2010-12-01T00:00:00Z
P5875
P6179
1019025470