Structure of the integrin binding fragment from fibrillin-1 gives new insights into microfibril organization
about
The evolution of extracellular fibrillins and their functional domainsStructure and interdomain interactions of a hybrid domain: a disulphide-rich module of the fibrillin/LTBP superfamily of matrix proteinsThe molecular genetics of Marfan syndrome and related disordersThe RGD finger of Del-1 is a unique structural feature critical for integrin bindingStructure of the Fibrillin-1 N-Terminal Domains Suggests that Heparan Sulfate Regulates the Early Stages of Microfibril AssemblyalphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificityADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formationAn assembly model of rift valley Fever virus.Tissue elasticity and the ageing elastic fibre.Biogenesis and function of fibrillin assemblies.Microfibril structure masks fibrillin-2 in postnatal tissuesMutations in fibrillin-1 cause congenital scleroderma: stiff skin syndrome.Multi-scale biomechanical remodeling in aging and genetic mutant murine mitral valve leaflets: insights into Marfan syndrome.Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactionsFibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.Nanostructure of fibrillin-1 reveals compact conformation of EGF arrays and mechanism for extensibility.Mutations in the TGFβ binding-protein-like domain 5 of FBN1 are responsible for acromicric and geleophysic dysplasias.ADAMTSL6β protein rescues fibrillin-1 microfibril disorder in a Marfan syndrome mouse model through the promotion of fibrillin-1 assembly.Fibrillin-containing microfibrils are key signal relay stations for cell function.Cell-matrix biology in vascular tissue engineering.Biogenesis of extracellular microfibrils: Multimerization of the fibrillin-1 C terminus into bead-like structures enables self-assemblyApplying elastic fibre biology in vascular tissue engineering.Extracellular matrix: from atomic resolution to ultrastructure.Fibrillin assembly requires fibronectin.Choreographing metastasis to the tune of LTBP.TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs.¹H, ¹³C and ¹⁵N resonance assignments for the fibrillin-1 EGF2-EGF3-hybrid1-cbEGF1 four-domain fragment.¹H, ¹³C and ¹⁵N assignments of the four N-terminal domains of human fibrillin-1.Fibrillin-1 interactions with heparin. Implications for microfibril and elastic fiber assembly.Selective integrin subunit reduction disrupts fibronectin extracellular matrix deposition and fibrillin 1 gene expression.(1)H, (13)C and (15)N assignments of EGF domains 8-11 of human Notch-1.A microfibril assembly assay identifies different mechanisms of dominance underlying Marfan syndrome, stiff skin syndrome and acromelic dysplasiasNMR spectroscopic and bioinformatic analyses of the LTBP1 C-terminus reveal a highly dynamic domain organisation.Fell-Muir Lecture: Fibrillin microfibrils: structural tensometers of elastic tissues?Early fibrillin-1 assembly monitored through a modifiable recombinant cell approach.Microfibrils and fibrillin-1 induce integrin-mediated signaling, proliferation and migration in human endothelial cells.Homotypic fibrillin-1 interactions in microfibril assembly.Modification of the structure and function of fibrillin-1 by homocysteine suggests a potential pathogenetic mechanism in homocystinuria.Marfan syndrome-causing mutations in fibrillin-1 result in gross morphological alterations and highlight the structural importance of the second hybrid domain.Ca2+-dependent interface formation in fibrillin-1.
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P2860
Structure of the integrin binding fragment from fibrillin-1 gives new insights into microfibril organization
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Structure of the integrin bind ...... into microfibril organization
@ast
Structure of the integrin bind ...... into microfibril organization
@en
Structure of the integrin bind ...... into microfibril organization
@en-gb
Structure of the integrin bind ...... into microfibril organization
@nl
type
label
Structure of the integrin bind ...... into microfibril organization
@ast
Structure of the integrin bind ...... into microfibril organization
@en
Structure of the integrin bind ...... into microfibril organization
@en-gb
Structure of the integrin bind ...... into microfibril organization
@nl
prefLabel
Structure of the integrin bind ...... into microfibril organization
@ast
Structure of the integrin bind ...... into microfibril organization
@en
Structure of the integrin bind ...... into microfibril organization
@en-gb
Structure of the integrin bind ...... into microfibril organization
@nl
P2093
P2860
P1433
P1476
Structure of the integrin bind ...... into microfibril organization
@en
P2093
Helen J Mardon
Jelena Jovanović
Jonathan M Grimes
Laurence Choulier
Penny A Handford
Stephen S J Lee
Vroni Knott
P2860
P304
P356
10.1016/J.STR.2004.02.023
P407
P577
2004-04-01T00:00:00Z