TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs.
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The evolution of extracellular fibrillins and their functional domainsGenetic and functional linkage between ADAMTS superfamily proteins and fibrillin-1: a novel mechanism influencing microfibril assembly and functionLatent TGF-β-binding proteinsStructure of the Fibrillin-1 N-Terminal Domains Suggests that Heparan Sulfate Regulates the Early Stages of Microfibril AssemblyCutis laxa: intersection of elastic fiber biogenesis, TGFβ signaling, the secretory pathway and metabolismTranscriptional profiling of the human fibrillin/LTBP gene family, key regulators of mesenchymal cell functions.C-terminal propeptide is required for fibrillin-1 secretion and blocks premature assembly through linkage to domains cbEGF41-43.Expression of FBN1 during adipogenesis: Relevance to the lipodystrophy phenotype in Marfan syndrome and related conditionsEMILIN2 regulates platelet activation, thrombus formation, and clot retraction.Specificity of latent TGF-β binding protein (LTBP) incorporation into matrix: role of fibrillins and fibronectinFibrillin-2, tenascin-C, matrilin-2, and matrilin-4 are strongly expressed in the epithelium of human granular and lattice type I corneal dystrophies.Fibrillin-containing microfibrils are key signal relay stations for cell function.Choreographing metastasis to the tune of LTBP.Unchaining the beast; insights from structural and evolutionary studies on TGFβ secretion, sequestration, and activationThe microfibril-associated glycoproteins (MAGPs) and the microfibrillar niche.LTBPs, more than just an escort service.The evolution of metazoan extracellular matrix.The microfibril hypothesis of glaucoma: implications for treatment of elevated intraocular pressure.¹H, ¹³C and ¹⁵N resonance assignments for the fibrillin-1 EGF2-EGF3-hybrid1-cbEGF1 four-domain fragment.¹H, ¹³C and ¹⁵N assignments of the four N-terminal domains of human fibrillin-1.Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins.Proteomic analysis of the extracellular matrix produced by mesenchymal stromal cells: implications for cell therapy mechanism.The N-Terminal Region of Fibrillin-1 Mediates a Bipartite Interaction with LTBP1.A microfibril assembly assay identifies different mechanisms of dominance underlying Marfan syndrome, stiff skin syndrome and acromelic dysplasiasNMR spectroscopic and bioinformatic analyses of the LTBP1 C-terminus reveal a highly dynamic domain organisation.Pathogenic Mechanisms of Bicuspid Aortic Valve Aortopathy.Fell-Muir Lecture: Fibrillin microfibrils: structural tensometers of elastic tissues?Regulation of TGFβ superfamily signaling by two separable domains of glypican LON-2 in C. elegans.Characterization of a novel missense mutation in the prodomain of GDF5, which underlies brachydactyly type C and mild Grebe type chondrodysplasia in a large Pakistani family.Backbone ¹H, ¹³C and ¹⁵N resonance assignment of the C-terminal EGF-cbEGF pair of LTBP1 and flanking residues.Gene expression and protein distribution of ADAMTSL-4 in human iris, choroid and retina.Two functional domains in C. elegans glypican LON-2 can independently inhibit BMP-like signaling.Elastin in lung development and disease pathogenesis.Mutations in LTBP3 cause acromicric dysplasia and geleophysic dysplasia.LTBP3 Pathogenic Variants Predispose Individuals to Thoracic Aortic Aneurysms and Dissections.Transglutaminase-2 promotes metastatic and stem-like phenotypes in osteosarcoma
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TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
TB domain proteins: evolutiona ...... roles of fibrillins and LTBPs.
@en
TB domain proteins: evolutiona ...... roles of fibrillins and LTBPs.
@nl
type
label
TB domain proteins: evolutiona ...... roles of fibrillins and LTBPs.
@en
TB domain proteins: evolutiona ...... roles of fibrillins and LTBPs.
@nl
prefLabel
TB domain proteins: evolutiona ...... roles of fibrillins and LTBPs.
@en
TB domain proteins: evolutiona ...... roles of fibrillins and LTBPs.
@nl
P2860
P356
P1433
P1476
TB domain proteins: evolutiona ...... roles of fibrillins and LTBPs.
@en
P2093
Penny Handford
P2860
P304
P356
10.1042/BJ20101320
P407
P577
2011-01-01T00:00:00Z