The N-terminal amphipathic alpha-helix of viperin mediates localization to the cytosolic face of the endoplasmic reticulum and inhibits protein secretion
about
The antiviral protein viperin is a radical SAM enzymeHuman cytomegalovirus directly induces the antiviral protein viperin to enhance infectivityViperin: a multifunctional, interferon-inducible protein that regulates virus replicationMechanistic and functional versatility of radical SAM enzymesThe antiviral protein viperin inhibits hepatitis C virus replication via interaction with nonstructural protein 5Aα-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8The antiviral protein, viperin, localizes to lipid droplets via its N-terminal amphipathic alpha-helixViperin restricts chikungunya virus replication and pathology.The interferon-inducible gene viperin restricts West Nile virus pathogenesisThe presence of the iron-sulfur motif is important for the conformational stability of the antiviral protein, ViperinViperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activityProtective efficacy of orally administered, heat-killed Lactobacillus pentosus b240 against influenza A virus.Viperin is induced following dengue virus type-2 (DENV-2) infection and has anti-viral actions requiring the C-terminal end of viperin.Fatty acid-binding protein E-FABP restricts tumor growth by promoting IFN-β responses in tumor-associated macrophages.Innate immunity to influenza virus infection.Identification of five interferon-induced cellular proteins that inhibit west nile virus and dengue virus infections.Intracellular innate immune cascades and interferon defenses that control hepatitis C virusViperin: a radical response to viral infectionEquine viperin restricts equine infectious anemia virus replication by inhibiting the production and/or release of viral Gag, Env, and receptor via distortion of the endoplasmic reticulum.ATR-FTIR spectroscopy reveals genomic loci regulating the tissue response in high fat diet fed BXD recombinant inbred mouse strains.Viperin regulates cellular lipid metabolism during human cytomegalovirus infectionActivation and evasion of antiviral innate immunity by hepatitis C virus.Monkey Viperin Restricts Porcine Reproductive and Respiratory Syndrome Virus ReplicationSystems Genetics of Obesity.Viperin interaction with mitochondrial antiviral signaling protein (MAVS) limits viperin-mediated inhibition of the interferon response in macrophagesEquine Infectious Anemia Virus Gag Assembly and Export Are Directed by Matrix Protein through trans-Golgi Networks and Cellular Vesicles.miR-200 family promotes podocyte differentiation through repression of RSAD2.Viperin inhibits rabies virus replication via reduced cholesterol and sphingomyelin and is regulated upstream by TLR4.Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium.Radical S-adenosylmethionine enzymes.The interferon inducible gene: ViperinViperin mRNA is a novel target for the human RNase MRP/RNase P endoribonuclease.Avian Interferons and Their Antiviral Effectors.Viperin, MTAP44, and protein kinase R contribute to the interferon-induced inhibition of Bunyamwera Orthobunyavirus replication.Cellular requirements for iron-sulfur cluster insertion into the antiviral radical SAM protein viperin.Structural studies of viperin, an antiviral radical SAM enzyme.Viperin is highly induced in neutrophils and macrophages during acute and chronic lymphocytic choriomeningitis virus infection.Porcine Viperin protein inhibits the replication of classical swine fever virus (CSFV) in vitro.Viperin targets flavivirus virulence by inducing assembly of non-infectious capsid particles.The radical-SAM enzyme Viperin catalyzes reductive addition of a 5'-deoxyadenosyl radical to UDP-glucose in vitro.
P2860
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P2860
The N-terminal amphipathic alpha-helix of viperin mediates localization to the cytosolic face of the endoplasmic reticulum and inhibits protein secretion
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The N-terminal amphipathic alp ...... and inhibits protein secretion
@ast
The N-terminal amphipathic alp ...... and inhibits protein secretion
@en
The N-terminal amphipathic alp ...... and inhibits protein secretion
@en-gb
The N-terminal amphipathic alp ...... and inhibits protein secretion
@nl
type
label
The N-terminal amphipathic alp ...... and inhibits protein secretion
@ast
The N-terminal amphipathic alp ...... and inhibits protein secretion
@en
The N-terminal amphipathic alp ...... and inhibits protein secretion
@en-gb
The N-terminal amphipathic alp ...... and inhibits protein secretion
@nl
prefLabel
The N-terminal amphipathic alp ...... and inhibits protein secretion
@ast
The N-terminal amphipathic alp ...... and inhibits protein secretion
@en
The N-terminal amphipathic alp ...... and inhibits protein secretion
@en-gb
The N-terminal amphipathic alp ...... and inhibits protein secretion
@nl
P2860
P921
P3181
P356
P1476
The N-terminal amphipathic alp ...... and inhibits protein secretion
@en
P2093
Ella R Hinson
Peter Cresswell
P2860
P304
P3181
P356
10.1074/JBC.M807261200
P407
P577
2009-02-13T00:00:00Z