RNA association and nucleocytoplasmic shuttling by ataxin-1
about
Ataxin-7 associates with microtubules and stabilizes the cytoskeletal network.The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1Cell biology of spinocerebellar ataxiaThe unstable repeats--three evolving faces of neurological diseasePolyglutamine expansion accelerates the dynamics of ataxin-1 and does not result in aggregate formation.Protein-protein interactions as a strategy towards protein-specific drug design: the example of ataxin-1Phosphorylation of S776 and 14-3-3 binding modulate ataxin-1 interaction with splicing factorsFAM46 proteins are novel eukaryotic non-canonical poly(A) polymerasesPractical three color live cell imaging by widefield microscopy.Formation and toxicity of soluble polyglutamine oligomers in living cells.CAG-encoded polyglutamine length polymorphism in the human genomeNucleocytoplasmic shuttling activity of ataxin-3.Ataxin-1 regulates epithelial-mesenchymal transition of cervical cancer cells.Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2.FOX-2 dependent splicing of ataxin-2 transcript is affected by ataxin-1 overexpressionStabilization and Degradation Mechanisms of Cytoplasmic Ataxin-1.Huntington's disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases.Regulation of microRNA expression by HMGA1 proteins.Partial loss of Tip60 slows mid-stage neurodegeneration in a spinocerebellar ataxia type 1 (SCA1) mouse model.Abnormalities in the climbing fiber-Purkinje cell circuitry contribute to neuronal dysfunction in ATXN1[82Q] miceRole of tissue transglutaminase type 2 in calbindin-D28k interaction with ataxin-1Tissue transglutaminase crosslinks ataxin-1: possible role in SCA1 pathogenesis.Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models.Amyloid oligomers: dynamics and toxicity in the cytosol and nucleus.Kaleidoscopic protein-protein interactions in the life and death of ataxin-1: new strategies against protein aggregation.Nuclear ataxias.Nucleolar aggresomes as counterparts of cytoplasmic aggresomes in proteotoxic stress. Proteasome inhibitors induce nuclear ribonucleoprotein inclusions that accumulate several key factors of neurodegenerative diseases and cancer.SCA1-phosphorylation, a regulator of Ataxin-1 function and pathogenesis.SUMO rules: regulatory concepts and their implication in neurologic functions.Neuroprotective function of 14-3-3 proteins in neurodegenerationFrom pathways to targets: understanding the mechanisms behind polyglutamine disease.RNA processing-associated molecular mechanisms of neurodegenerative diseases.Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).SUMOylation of the polyglutamine repeat protein, ataxin-1, is dependent on a functional nuclear localization signal.Phosphorylation of ATXN1 at Ser776 in the cerebellum.Ataxin-7 can export from the nucleus via a conserved exportin-dependent signal.Polyglutamine spinocerebellar ataxias - from genes to potential treatments.Tung tree DGAT1 and DGAT2 have nonredundant functions in triacylglycerol biosynthesis and are localized to different subdomains of the endoplasmic reticulum.Ion channel dysfunction in cerebellar ataxia.Accumulation of the sigma-1 receptor is common to neuronal nuclear inclusions in various neurodegenerative diseases.
P2860
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P248
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P2860
RNA association and nucleocytoplasmic shuttling by ataxin-1
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
RNA association and nucleocytoplasmic shuttling by ataxin-1
@ast
RNA association and nucleocytoplasmic shuttling by ataxin-1
@en
RNA association and nucleocytoplasmic shuttling by ataxin-1
@en-gb
RNA association and nucleocytoplasmic shuttling by ataxin-1
@nl
type
label
RNA association and nucleocytoplasmic shuttling by ataxin-1
@ast
RNA association and nucleocytoplasmic shuttling by ataxin-1
@en
RNA association and nucleocytoplasmic shuttling by ataxin-1
@en-gb
RNA association and nucleocytoplasmic shuttling by ataxin-1
@nl
prefLabel
RNA association and nucleocytoplasmic shuttling by ataxin-1
@ast
RNA association and nucleocytoplasmic shuttling by ataxin-1
@en
RNA association and nucleocytoplasmic shuttling by ataxin-1
@en-gb
RNA association and nucleocytoplasmic shuttling by ataxin-1
@nl
P2093
P921
P3181
P356
P1476
RNA association and nucleocytoplasmic shuttling by ataxin-1
@en
P2093
Deborah Pinchev
Jenny L Howell
Joanna Graczyk
Ray Truant
Stuart Irwin
P304
P3181
P356
10.1242/JCS.01611
P407
P577
2005-01-01T00:00:00Z