Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.
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Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysisThe Role of G-Protein-Coupled Receptor Proteolysis Site Cleavage of Polycystin-1 in Renal Physiology and Polycystic Kidney DiseaseRole of the Polycystins in Cell Migration, Polarity, and Tissue MorphogenesisWnt and planar cell polarity signaling in cystic renal diseasePolycystin-1 cleavage and the regulation of transcriptional pathwaysOFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblastsStepwise Evolution of Coral Biomineralization Revealed with Genome-Wide Proteomics and TranscriptomicsInternational Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptorsActivation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomainsRegulation of calcium signaling by polycystin-2Sticky signaling--adhesion class G protein-coupled receptors take the stageGPS autoproteolysis is required for CD97 to up-regulate the expression of N-cadherin that promotes homotypic cell-cell aggregationMechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminusA genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formationFunction and dynamics of PKD2 in Chlamydomonas reinhardtii flagella.Polyductin undergoes notch-like processing and regulated release from primary ciliaPolycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion.The 10 sea urchin receptor for egg jelly proteins (SpREJ) are members of the polycystic kidney disease-1 (PKD1) familyA novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.Conditional disruption of Pkd1 in osteoblasts results in osteopenia due to direct impairment of bone formation.Identification of a polycystin-1 cleavage product, P100, that regulates store operated Ca entry through interactions with STIM1.Polycystic kidney disease.Determinants of renal disease variability in ADPKD.Molecular advances in autosomal dominant polycystic kidney disease.Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease.A missense mutation in PKD1 attenuates the severity of renal diseaseCyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.Novel functional complexity of polycystin-1 by GPS cleavage in vivo: role in polycystic kidney diseaseRole of the polycytin-primary cilia complex in bone development and mechanosensingMolecular diagnostics for autosomal dominant polycystic kidney diseaseThe cell biology of polycystic kidney diseaseProteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif.GPR56 and the developing cerebral cortex: cells, matrix, and neuronal migrationEvidence of a third ADPKD locus is not supported by re-analysis of designated PKD3 families.Polycystin-1 surface localization is stimulated by polycystin-2 and cleavage at the G protein-coupled receptor proteolytic site.ADPKD: Prototype of Cardiorenal Syndrome Type 4Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver DiseaseCiliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanismAberrant glycosylation and localization of polycystin-1 cause polycystic kidney in an AQP11 knockout model.
P2860
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P2860
Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Cleavage of polycystin-1 requi ...... disease 1-associated mutations
@nl
Cleavage of polycystin-1 requi ...... isease 1-associated mutations.
@ast
Cleavage of polycystin-1 requi ...... isease 1-associated mutations.
@en
Cleavage of polycystin-1 requi ...... isease 1-associated mutations.
@en-gb
type
label
Cleavage of polycystin-1 requi ...... disease 1-associated mutations
@nl
Cleavage of polycystin-1 requi ...... isease 1-associated mutations.
@ast
Cleavage of polycystin-1 requi ...... isease 1-associated mutations.
@en
Cleavage of polycystin-1 requi ...... isease 1-associated mutations.
@en-gb
prefLabel
Cleavage of polycystin-1 requi ...... disease 1-associated mutations
@nl
Cleavage of polycystin-1 requi ...... isease 1-associated mutations.
@ast
Cleavage of polycystin-1 requi ...... isease 1-associated mutations.
@en
Cleavage of polycystin-1 requi ...... isease 1-associated mutations.
@en-gb
P2093
P2860
P921
P3181
P356
P1476
Cleavage of polycystin-1 requi ...... disease 1-associated mutations
@en
P2093
Alessandra Boletta
Ali K Ahrabi
Anil K Bhunia
Hangxue Xu
Lijuan Liu
Terry J Watnick
P2860
P304
16981-16986
P3181
P356
10.1073/PNAS.252484899
P407
P577
2002-12-13T00:00:00Z