The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling
about
Identification of a family of sorting nexin molecules and characterization of their association with receptorsCloning and characterization of PRAX-1. A new protein that specifically interacts with the peripheral benzodiazepine receptorSHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activationIdentification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptorA phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cellsUse of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasisMAPK scaffold IQGAP1 binds the EGF receptor and modulates its activationThe Grb2/PLD2 interaction is essential for lipase activity, intracellular localization and signaling in response to EGFSubcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca2+ signaling in B cellsThe elucidation of novel SH2 binding sites on PLD2Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteinsHierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptorPhosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivoSelected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptorActivation of Src family kinases by colony stimulating factor-1, and their association with its receptorActivation of extracellular signal-regulated kinase 2 by a novel Abl-binding protein, ST5SH3 domains of Grb2 adaptor bind to PXpsiPXR motifs within the Sos1 nucleotide exchange factor in a discriminate mannerThe 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase SypThe product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent mannerTwo signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptorThe role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signalingMolecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cellsp70 phosphorylation and binding to p56lck is an early event in interleukin-2-induced onset of cell cycle progression in T-lymphocytesComplete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2Association of csk-homologous kinase (CHK) (formerly MATK) with HER-2/ErbB-2 in breast cancer cellsSpecific phosphopeptide binding regulates a conformational change in the PI 3-kinase SH2 domain associated with enzyme activationThe phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor proteinGrap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathwayA Ras-GTPase-activating protein SH3-domain-binding proteinIntroduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinasesGrowth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signalingRole of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesisHuman deltex is a conserved regulator of Notch signallingBivalent binding drives the formation of the Grb2-Gab1 signaling complex in a noncooperative mannerA novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent mannerAnalysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3Rapid identification of phosphopeptide ligands for SH2 domains. Screening of peptide libraries by fluorescence-activated bead sortingDifferential interactions of human Sos1 and Sos2 with Grb2NMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from Sos
P2860
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P2860
The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling
description
1992 nî lūn-bûn
@nan
1992 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@ast
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@en
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@en-gb
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@nl
type
label
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@ast
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@en
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@en-gb
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@nl
prefLabel
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@ast
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@en
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@en-gb
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@nl
P2093
P921
P3181
P1433
P1476
The SH2 and SH3 domain-contain ...... osine kinases to ras signaling
@en
P2093
A G Batzer
B Margolis
D Bar-Sagi
E J Lowenstein
E Y Skolnik
J Schlessinger
P304
P3181
P356
10.1016/0092-8674(92)90167-B
P407
P577
1992-08-07T00:00:00Z