Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis
about
Control of mitochondrial morphology through differential interactions of mitochondrial fusion and fission proteinsBcl-2 family interaction with the mitochondrial morphogenesis machineryInteraction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosisLoss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerizationDysregulation of HSG triggers vascular proliferative disordersIBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activationQuantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosisMitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescenceSIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stressThe mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial divisionLoss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fissionIdentification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylationEndoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis.Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosisRoles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosisNew insights into the role of mitochondria in aging: mitochondrial dynamics and moreCytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR foldThe mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosisEndophilin B1 is required for the maintenance of mitochondrial morphologyAltered Traffic of Cardiolipin during Apoptosis: Exposure on the Cell Surface as a Trigger for "Antiphospholipid Antibodies"Mitochondrial dynamics in cardiovascular health and diseasePhysiological and pathological significance of dynamin-related protein 1 (drp1)-dependent mitochondrial fission in the nervous systemCell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative diseasePathologic and therapeutic implications for the cell biology of parkinMechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress.Mitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degenerationBH3 peptides induce mitochondrial fission and cell death independent of BAX/BAKA mutation associated with CMT2A neuropathy causes defects in Fzo1 GTP hydrolysis, ubiquitylation, and protein turnover.Mitochondrial fusion and fission proteins as novel therapeutic targets for treating cardiovascular diseaseKnockdown of MTP18, a novel phosphatidylinositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosisMitochondrial fragmentation in neurodegenerationBuilding blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosisShaping the role of mitochondria in the pathogenesis of Huntington's diseaseSpecific interaction with cardiolipin triggers functional activation of Dynamin-Related Protein 1Cell biology. Metabolic control of cell deathModeling a snap-action, variable-delay switch controlling extrinsic cell deathAtad3 function is essential for early post-implantation development in the mouseSpatial and temporal changes in Bax subcellular localization during anoikis
P2860
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P2860
Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@ast
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@en
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@en-gb
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@nl
type
label
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@ast
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@en
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@en-gb
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@nl
prefLabel
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@ast
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@en
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@en-gb
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@nl
P2093
P2860
P921
P3181
P356
P1476
Spatial and temporal associati ...... rp1, and Mfn2 during apoptosis
@en
P2093
Amotz Nechushtan
Ansgar Santel
Brigitte Gaume
Carolyn L Smith
Mariusz Karbowski
Richard J Youle
Seon-Yong Jeong
Stephan Frank
Yang-Ja Lee
P2860
P304
P3181
P356
10.1083/JCB.200209124
P407
P50
P577
2002-12-23T00:00:00Z