Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis - sprookjes - yvandenbroek - TriplyDB

Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

http://www.wikidata.org/entity/Q24562044

about

Control of mitochondrial morphology through differential interactions of mitochondrial fusion and fission proteins MARCH5 inactivation supports mitochondrial function during neurodegenerative stress Mitofusin 1 is degraded at G2/M phase through ubiquitylation by MARCH5 Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1 Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization MARCH-V is a novel mitofusin 2- and Drp1-binding protein able to change mitochondrial morphology Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence hNOA1 interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosis Identification and characterization of unique proline-rich peptides binding to the mitochondrial fission protein hFis1 The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission.The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction Endophilin B1/Bif-1 stimulates BAX activation independently from its capacity to produce large scale membrane morphological rearrangements Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis.New insights into the role of mitochondria in aging: mitochondrial dynamics and more Novel therapeutics for Alzheimer's disease: an update An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria The mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosis Novel Insights into Insect-Microbe Interactions-Role of Epigenomics and Small RNAs Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease Cross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and Disease Alterations in Mitochondrial Quality Control in Alzheimer's Disease Mitochondrial Quality Control and Muscle Mass Maintenance Mitochondrial dysfunction in inflammatory bowel disease Mitochondrial dynamics in cardiovascular health and disease Cell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative disease Heart failure and mitochondrial dysfunction: the role of mitochondrial fission/fusion abnormalities and new therapeutic strategies Morphological control of mitochondrial bioenergetics Mechanisms of mitochondria and autophagy crosstalk Cell cycle regulators guide mitochondrial activity in radiation-induced adaptive response Mitochondrial dysfunction and sarcopenia of aging: from signaling pathways to clinical trials The C. elegans Opa1 homologue EAT-3 is essential for resistance to free radicals The molecular mechanisms of OPA1-mediated optic atrophy in Drosophila model and prospects for antioxidant treatment Human wild-type full-length tau accumulation disrupts mitochondrial dynamics and the functions via increasing mitofusins.

P2860

Q21091032-41DBA997-B3C2-4231-96C0-B84481F8EA71 Q21129482-EFBE589A-3936-47E2-BD8F-60687C43DA50 Q21203545-13CBEA74-AB69-4EE1-ACFE-F99D0343C2EA Q24297466-31D9A7DC-EF12-4AEC-A59F-ED514DB43A6D Q24300125-CF8B5168-E2AB-4292-BE92-9CB610BE9B6B Q24300832-0790BF19-4700-4DFF-B762-48E3122AB24B Q24307570-849E7A5D-5BB6-4A0D-9ADB-B8C173DCCA62 Q24307740-5B0A3362-A39B-44A6-BA1E-EF40EA983D25 Q24307751-02676FA4-5F3A-4187-8C9E-8DD9EF1BDE42 Q24310217-6CFD89BD-1105-4FC2-B42E-78F6C344AEF3 Q24311781-7AC6B1B9-C4A5-4B7F-8C9A-CCF0E52C7DF8 Q24312865-B8D7358C-01E3-43DB-9565-D1AC669BD5E7 Q24315625-12FA7E92-A0E3-4EB5-8970-BAEF0BEBE498 Q24315659-F313A0C1-AC21-45EB-9193-B74F067ACB4A Q24316439-11F5D769-DD04-4A5A-AC33-7D57E55B5098 Q24320479-56EA0829-DD47-4F85-8F92-D67E22DCB0E1 Q24324817-04054128-776B-447D-A954-B77D43C30393 Q24336889-E5E14ED0-3B15-4669-BCED-0A3C53FB887D Q24529124-5C8479A9-86EB-4237-998B-A5ECC3281AF5 Q24600600-97BFF06E-0DC8-42B8-9BD4-694620E4DAC9 Q24620383-92B5F599-BDD6-45D0-BB39-90475D040EBE Q24630079-35AE6463-24E6-41B9-B37F-85826A701A8D Q24631535-DCC488B0-D14C-49EB-B5E3-7A62AB5943DE Q24673883-E5157A12-C6D1-4565-B24E-DE655E769A0E Q26700139-07E57DEA-48E9-43B7-A75E-18428CB3B93B Q26744105-22EAFDE6-5632-4764-B516-A5832E96277F Q26765684-66844301-C0CC-4F71-B475-32B9E78EE3F7 Q26768215-3ACB04C1-515B-4BA0-BC44-116C62A2BABA Q26770420-AD48EB3D-D2F5-4A75-8563-0441382FB69C Q26781311-C3FB741B-8FA9-4649-9C5C-74BF28B36CBA Q26820835-5A77C969-B84B-4B3A-A276-CBE169B62844 Q26853356-5B6B5CB3-824B-4238-8369-45EB88547BF4 Q27005955-D164D58D-8DD3-474C-A755-901C77D1326B Q27006036-88C80A2D-0446-4571-97FC-117E589938AB Q27011830-614AE0B7-F7B9-4F60-A2F3-2CCB682CA0B1 Q27014767-169B4AA2-4199-4166-87A0-E0667370CED1 Q27022354-FEB06408-1A9C-4176-8DDD-05437CB1DAA3 Q27314280-61279F39-1539-40C6-81A2-94B02CEFBC45 Q27314564-DE3C2372-456D-46EA-B88F-339333B38DB5 Q27320038-061E51A9-7B72-41C0-8BF1-133F9DED1698

P2860

Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

http://www.wikidata.org/entity/Q24562044

description

2004 nî lūn-bûn

@nan

2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Roles of the mammalian mitocho ...... 1, Drp1, and Opa1 in apoptosis

@ast

Roles of the mammalian mitocho ...... 1, Drp1, and Opa1 in apoptosis

@en

Roles of the mammalian mitocho ...... 1, Drp1, and Opa1 in apoptosis

@nl

type

label

Roles of the mammalian mitocho ...... 1, Drp1, and Opa1 in apoptosis

@ast

Roles of the mammalian mitocho ...... 1, Drp1, and Opa1 in apoptosis

@en

Roles of the mammalian mitocho ...... 1, Drp1, and Opa1 in apoptosis

@nl

prefLabel

Roles of the mammalian mitocho ...... 1, Drp1, and Opa1 in apoptosis

@ast

Roles of the mammalian mitocho ...... 1, Drp1, and Opa1 in apoptosis

@en

Roles of the mammalian mitocho ...... 1, Drp1, and Opa1 in apoptosis

@nl

P1433

Q24562044-659C2B6D-86F4-4F32-B5E5-55874C2D0BC0

P1476

Q24562044-E235822D-7A73-48DF-AFB3-9E7D1979283E

P2093

Q24562044-4FDC1D24-A613-4274-B2DA-D5E054D2EC0A

Q24562044-68331E25-DE39-4AE3-B391-67DB991164E1

Q24562044-867AB102-924B-4D9E-B6AC-1BED87171E8E

Q24562044-941C3A4A-4201-450E-A969-6210AD342613

Q24562044-D038F54D-E053-4227-82AB-90FE3C6A46C1

P2860

Q24562044-072DB25D-2808-43FB-9ADF-5AE630D4ED18

Q24562044-0812B96C-C627-49AD-AA46-735AB06AEAAA

Q24562044-1458CB62-8512-440B-B827-9BFD493B9D24

Q24562044-292BDDC2-4927-4503-97B7-D402616DBBEA

Q24562044-2A468CDA-B3EA-4A61-878B-04E1BA698CDA

Q24562044-3054C015-0570-4F7C-85DE-3323757DEC7E

Q24562044-316329D8-177B-4F27-AB31-7DA3CF695789

Q24562044-3B146122-ECAB-4F3E-AE74-FEEB5831F58D

Q24562044-3C41543E-2E5F-40CA-A904-BAC09EE6CC7E

Q24562044-4A508FF1-AA17-4140-8408-F038F9F19838

P304

Q24562044-5E74FCEA-2793-4BAF-B56B-6B57BCC065BC

P31

Q24562044-38547059-DF15-4139-9E7E-2284D791308E

P3181

Q24562044-CC2848DF-D4B6-4789-A868-C1F83165C772

P356

Q24562044-BC4E273D-564B-4252-801D-8A0B37006F0E

P407

Q24562044-432B35C3-1F58-446E-80C1-0BFDB66DEA96

P433

Q24562044-A157DB9F-8829-4BCE-8113-5588FF42FBDB

P478

Q24562044-31D10668-E335-4FDE-880C-9166BF928267

P577

Q24562044-F9577AB6-ADD7-4ED6-9871-600A60F2A87D

P5875

Q24562044-8868CE1A-EA69-4DFD-97BF-98863FB5B350

P698

Q24562044-BACC341E-BE0C-4928-A909-D1479628C4FD

P921

Q24562044-315C8A01-7905-46C7-B92B-BEB4E75489BF

Q24562044-9447F653-9CF0-46BB-9AD6-FA6ED364C6D2

Q24562044-B44823C1-F619-4D50-8D84-C7F793019C9C

P932

Q24562044-611F990D-E120-4FB2-9F1F-E356E3949D50

P3181

P356

MBC.E04-04-0294

P1433

Molecular Biology of the Cell

P1476

Roles of the mammalian mitocho ...... 1, Drp1, and Opa1 in apoptosis

@en

P2093

Carolyn L Smith

http://www.w3.org/2001/XMLSchema#string

Mariusz Karbowski

http://www.w3.org/2001/XMLSchema#string

Richard J Youle

http://www.w3.org/2001/XMLSchema#string

Seon-Yong Jeong

http://www.w3.org/2001/XMLSchema#string

Yang-ja Lee

http://www.w3.org/2001/XMLSchema#string

P2860

OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

Control of mitochondrial morphology by a human mitofusin

Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells

Cellular localization, oligomerization, and membrane association of the hereditary spastic paraplegia 3A (SPG3A) protein atlastin

Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis

The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1

Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

P304

5001-11

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1367803

http://www.w3.org/2001/XMLSchema#string

P356

10.1091/MBC.E04-04-0294

http://www.w3.org/2001/XMLSchema#string

P407

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

15

http://www.w3.org/2001/XMLSchema#string

P577

2004-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8358309

http://www.w3.org/2001/XMLSchema#string

P698

15356267

http://www.w3.org/2001/XMLSchema#string

P921

apoptotic process

P932

524759

http://www.w3.org/2001/XMLSchema#string